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Fibrinogen, social position, and risk of heart disease
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  • Published on:
    Re: Fibrinogen, social position and "Mendelian randomization"
    • John Macleod, Senior Lecturer
    • Other Contributors:
      • George Davey Smith

    Dear Editor

    Jousilahti and Salomaa appear unhappy with our response to their paper on the social patterning of serum inflammatory markers.

    First they feel that we have misinterpreted their findings and conclusions. We fail to see how. They found (as others have) that social disadvantage was associated with increased inflammation – as indexed by markers such as higher fibrinogen - and that this association...

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    Conflict of Interest:
    None declared.
  • Published on:
    Fibrinogen, social position and "Mendelian randomization"

    Dear Editor

    We appreciate the comments of Macleod and Davey-Smith on our recent article reporting an association between systemic inflammation markers and socio-economic status.[1,2] In their letter, Macleod and Davey-Smith state that our findings, particularly the association of fibrinogen with socio-economic status, and its interpretation is not correct, and runs contrary to the principle of "Mendelian randomisat...

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    Conflict of Interest:
    None declared.