COVID-19, which is caused by SARS-CoV-2, can result in acute respiratory distress
syndrome and multiple organ failure,,–, but little is known about its pathophysiology. Here …

Renal insufficiency is characterised by impaired host defences, which are compromised
further by each of the 3 modes of renal replacement—haemodialysis, continuous ambulatory …

Heart failure encompasses a heterogeneous set of clinical features that converge on
impaired cardiac contractile function, and presents a growing public health concern …

Background: The human heart requires a complex ensemble of specialized cell types to
perform its essential function. A greater knowledge of the intricate cellular milieu of the heart …

Gliomas account for approximately 80% of all primary malignant brain tumors and, despite
improvements in clinical care over the last 20 years, remain among the most lethal tumors …

Genome-wide association studies (GWAS) have transformed our understanding of glioma
susceptibility, but individual studies have had limited power to identify risk loci. We …

This volume presents contemporary evidence scientific, archaeological, botanical, textual,
and historical for major revisions in our understanding of winemaking in antiquity. Among …

Enlargement or aneurysm of the aorta predisposes to dissection, an important cause of
sudden death. We trained a deep learning model to evaluate the dimensions of the …

Droplet-based scRNA-seq assays are known to produce a significant amount of background
RNA counts, the hallmark of which is non-zero transcript counts in presumably empty …

Previous genome-wide association studies (GWASs) have shown that common genetic
variation contributes to the heritable risk of glioma. To identify new glioma susceptibility loci …