User profiles for "author:Paul Blanche"

Paul Blanche

Section of Biostatistics, Department of Public Health, University of Copenhagen
Verified email at sund.ku.dk
Cited by 2758

Circulating tumor cells in breast cancer patients treated by neoadjuvant chemotherapy: a meta-analysis

FC Bidard, S Michiels, S Riethdorf… - JNCI: Journal of the …, 2018 - academic.oup.com
Background We conducted a meta-analysis in nonmetastatic breast cancer patients treated
by neoadjuvant chemotherapy (NCT) to assess the clinical validity of circulating tumor cell …

Estimating and comparing time‐dependent areas under receiver operating characteristic curves for censored event times with competing risks

P Blanche, JF Dartigues… - Statistics in …, 2013 - Wiley Online Library
The area under the time‐dependent ROC curve (AUC) may be used to quantify the ability of
a marker to predict the onset of a clinical outcome in the future. For survival analysis with …

Concordance for prognostic models with competing risks

M Wolbers, P Blanche, MT Koller, JCM Witteman… - …, 2014 - academic.oup.com
The concordance probability is a widely used measure to assess discrimination of
prognostic models with binary and survival endpoints. We formally define the concordance …

Quantifying and comparing dynamic predictive accuracy of joint models for longitudinal marker and time‐to‐event in presence of censoring and competing risks

P Blanche, C Proust‐Lima, L Loubère, C Berr… - …, 2015 - Wiley Online Library
Thanks to the growing interest in personalized medicine, joint modeling of longitudinal
marker and time‐to‐event data has recently started to be used to derive dynamic individual …

The c-index is not proper for the evaluation of -year predicted risks

P Blanche, MW Kattan, TA Gerds - Biostatistics, 2019 - academic.oup.com
We show that the widely used concordance index for time to event outcome is not proper
when interest is in predicting a-year risk of an event, for example 10-year mortality. In the …

Time-dependent AUC with right-censored data: a survey

P Blanche, A Latouche, V Viallon - Risk assessment and evaluation of …, 2013 - Springer
The ROC curve and the corresponding AUC are popular tools for the evaluation of
diagnostic tests. They have been recently extended to assess prognostic markers and …

Review and comparison of ROC curve estimators for a time‐dependent outcome with marker‐dependent censoring

P Blanche, JF Dartigues… - Biometrical Journal, 2013 - Wiley Online Library
To quantify the ability of a marker to predict the onset of a clinical outcome in the future, time‐
dependent estimators of sensitivity, specificity, and ROC curve have been proposed …

Effect of long-term beta-blocker treatment following myocardial infarction among stable, optimally treated patients without heart failure in the reperfusion era: a Danish …

A Holt, P Blanche, B Zareini, D Rajan… - European heart …, 2021 - academic.oup.com
Aims We aimed to investigate the long-term cardio-protective effect associated with beta-
blocker (BB) treatment in stable, optimally treated myocardial infarction (MI) patients without …

The risk of healing complications in primary teeth with intrusive luxation: a retrospective cohort study

E Lauridsen, P Blanche, N Yousaf… - Dental …, 2017 - Wiley Online Library
Abstract Background/Aims Intrusive luxation is a frequent injury in the primary dentition.
Complications such as ankylosis or pulp necrosis (PN) and infection with periapical …

Type 2 diabetes mellitus and impact of heart failure on prognosis compared to other cardiovascular diseases: a nationwide study

B Zareini, P Blanche, M D'Souza… - … Quality and Outcomes, 2020 - Am Heart Assoc
Background: Heart failure (HF) in patients with type 2 diabetes mellitus (T2D) has received
growing attention. We examined the effect of HF development on prognosis compared with …