[HTML][HTML] Comorbidities, multimorbidity and COVID-19

CD Russell, NI Lone, JK Baillie - Nature medicine, 2023 - nature.com
The influence of comorbidities on COVID-19 outcomes has been recognized since the
earliest days of the pandemic. But establishing causality and determining underlying …

Society of Critical Care Medicine's international consensus conference on prediction and identification of long-term impairments after critical illness

ME Mikkelsen, M Still, BJ Anderson… - Critical care …, 2020 - journals.lww.com
Background: After critical illness, new or worsening impairments in physical, cognitive,
and/or mental health function are common among patients who have survived. Who should …

Respiratory sequelae of COVID-19: pulmonary and extrapulmonary origins, and approaches to clinical care and rehabilitation

SJ Singh, MM Baldwin, E Daynes, RA Evans… - The Lancet …, 2023 - thelancet.com
Although the exact prevalence of post-COVID-19 condition (also known as long COVID) is
unknown, more than a third of patients with COVID-19 develop symptoms that persist for …

[HTML][HTML] Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study

RA Evans, H McAuley, EM Harrison… - The Lancet …, 2021 - thelancet.com
Background The impact of COVID-19 on physical and mental health and employment after
hospitalisation with acute disease is not well understood. The aim of this study was to …

[HTML][HTML] Acute blood biomarker profiles predict cognitive deficits 6 and 12 months after COVID-19 hospitalization

M Taquet, Z Skorniewska, A Hampshire… - Nature medicine, 2023 - nature.com
Post-COVID cognitive deficits, including 'brain fog', are clinically complex, with both objective
and subjective components. They are common and debilitating, and can affect the ability to …

[HTML][HTML] Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective …

RA Evans, OC Leavy, M Richardson… - The Lancet …, 2022 - thelancet.com
Background No effective pharmacological or non-pharmacological interventions exist for
patients with long COVID. We aimed to describe recovery 1 year after hospital discharge for …

[HTML][HTML] Prolonged mechanical ventilation in critically ill patients: epidemiology, outcomes and modelling the potential cost consequences of establishing a regional …

NI Lone, TS Walsh - Critical Care, 2011 - Springer
Introduction The number of patients requiring prolonged mechanical ventilation (PMV) is
likely to increase. Transferring patients to specialised weaning units may improve outcomes …

Five-year mortality and hospital costs associated with surviving intensive care

NI Lone, MA Gillies, C Haddow, R Dobbie… - American journal of …, 2016 - atsjournals.org
Rationale: Survivors of critical illness experience significant morbidity, but the impact of
surviving the intensive care unit (ICU) has not been quantified comprehensively at a …

Physical, cognitive and mental health impacts of COVID-19 following hospitalisation–a multi-centre prospective cohort study

PHOSP-COVID Collaborative Group, RA Evans… - MedRxiv, 2021 - medrxiv.org
Background The impact of COVID-19 on physical and mental health, and employment
following hospitalisation is poorly understood. Methods PHOSP-COVID is a multi-centre, UK …

[HTML][HTML] Changes in in-hospital mortality in the first wave of COVID-19: a multicentre prospective observational cohort study using the WHO Clinical Characterisation …

AB Docherty, RH Mulholland, NI Lone… - The Lancet …, 2021 - thelancet.com
Background Mortality rates in hospitalised patients with COVID-19 in the UK appeared to
decline during the first wave of the pandemic. We aimed to quantify potential drivers of this …