The power of genetic diversity in genome-wide association studies of lipids

SE Graham, SL Clarke, KHH Wu, S Kanoni, GJM Zajac… - Nature, 2021 - nature.com
Increased blood lipid levels are heritable risk factors of cardiovascular disease with varied
prevalence worldwide owing to different dietary patterns and medication use. Despite …

Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation

IE Christophersen, M Rienstra, C Roselli, X Yin… - Nature …, 2017 - nature.com
Atrial fibrillation affects more than 33 million people worldwide and increases the risk of
stroke, heart failure, and death,. Fourteen genetic loci have been associated with atrial …

Incidence of second cancers after radiotherapy and systemic chemotherapy in heritable retinoblastoma survivors: a report from the German reference center

P Temming, M Arendt, A Viehmann… - Pediatric blood & …, 2017 - Wiley Online Library
Background Survivors of heritable retinoblastoma carry a high risk to develop second
cancers. Eye‐preserving radiotherapy raises this risk, while the impact of chemotherapy …

Shift work and the incidence of prostate cancer: a 10-year follow-up of a German population-based cohort study

T Behrens, S Rabstein, K Wichert, R Erbel… - Scandinavian journal of …, 2017 - JSTOR
Objectives We investigated the association of shift and night work with the incidence of
prostate cancer using data of the population-based prospective Heinz Nixdorf Recall Study …

[PDF][PDF] How eye-preserving therapy affects long-term overall survival in heritable retinoblastoma survivors

P Temming, M Arendt, A Viehmann, L Eisele… - J Clin Oncol, 2016 - academia.edu
Purpose Intraocular retinoblastoma is curable, but survivors with a heritable predisposition
are at high risk for second malignancies. Because second malignancies are associated with …

Impact of shift work on the risk of depression

T Behrens, K Burek, S Rabstein, K Wichert… - Chronobiology …, 2021 - Taylor & Francis
We studied the association between shift work and depressive symptoms in the prospective
Heinz Nixdorf Recall Study, considering various demographic, lifestyle and work-related …

The distribution of blood concentrations of lead (Pb), cadmium (Cd), chromium (Cr) and manganese (Mn) in residents of the German Ruhr area and its potential …

N Bonberg, B Pesch, N Ulrich, S Moebus… - International Journal of …, 2017 - Elsevier
Objective This study investigated the metal distribution in blood samples from the general
population and the risk of having high metal concentration for metal workers. Methods Metal …

Prolongation of the QTc interval in HIV-infected individuals compared to the general population

N Reinsch, M Arendt, MH Geisel, C Schulze… - Infection, 2017 - Springer
Objectives Prolonged QT interval is associated with arrhythmias and sudden death. An
increased prevalence of QT interval prolongation in human immunodeficiency virus-infected …

Pediatric second primary malignancies after retinoblastoma treatment

P Temming, A Viehmann, M Arendt… - Pediatric blood & …, 2015 - Wiley Online Library
Background Children with retinoblastoma carry a high risk to develop second primary
malignancies in childhood and adolescence. This study characterizes the type of pediatric …

[HTML][HTML] Agreement of self-reported and administrative data on employment histories in a German cohort study: a sequence analysis

M Wahrendorf, A Marr, M Antoni, B Pesch… - European Journal of …, 2019 - Springer
Collecting life course data is increasingly common in social and epidemiological research,
either through record linkage of administrative data or by collecting retrospective interview …