User profiles for "author:Leah M Smith"
Leah M. SmithUniversity of Otago Verified email at otago.ac.nz Cited by 174 |
Projected estimates of cancer in Canada in 2020
DR Brenner, HK Weir, AA Demers, LF Ellison… - Cmaj, 2020 - Can Med Assoc
BACKGROUND: Cancer projections to the current year help in policy development, planning
of programs and allocation of resources. We sought to provide an overview of the expected …
of programs and allocation of resources. We sought to provide an overview of the expected …
Effect of human papillomavirus (HPV) vaccination on clinical indicators of sexual behaviour among adolescent girls: the Ontario Grade 8 HPV Vaccine Cohort Study
LM Smith, JS Kaufman, EC Strumpf, LE Lévesque - Cmaj, 2015 - Can Med Assoc
Background: Suboptimal human papillomavirus (HPV) vaccine coverage in some
jurisdictions is partly attributed to fears that vaccination may increase risky sexual behaviour …
jurisdictions is partly attributed to fears that vaccination may increase risky sexual behaviour …
[PDF][PDF] Type III CRISPR-Cas provides resistance against nucleus-forming jumbo phages via abortive infection
Bacteria have diverse defenses against phages. In response, jumbo phages evade multiple
DNA-targeting defenses by protecting their DNA inside a nucleus-like structure. We …
DNA-targeting defenses by protecting their DNA inside a nucleus-like structure. We …
SorTn-seq: a high-throughput functional genomics approach to discovering regulators of bacterial gene expression
We recently developed a high-throughput functional genomics approach, named 'SorTn-
seq', to identify factors affecting expression of any gene of interest in bacteria. Our approach …
seq', to identify factors affecting expression of any gene of interest in bacteria. Our approach …
The early benefits of human papillomavirus vaccination on cervical dysplasia and anogenital warts
BACKGROUND: Despite widespread promotion of quadrivalent human papillomavirus
(qHPV) vaccination for young girls, there is limited information on the vaccine's real-world …
(qHPV) vaccination for young girls, there is limited information on the vaccine's real-world …
The Rcs stress response inversely controls surface and CRISPR–Cas adaptive immunity to discriminate plasmids and phages
Bacteria harbour multiple innate defences and adaptive CRISPR–Cas systems that provide
immunity against bacteriophages and mobile genetic elements. Although some bacteria …
immunity against bacteriophages and mobile genetic elements. Although some bacteria …
The autoregulator Aca2 mediates anti-CRISPR repression
CRISPR-Cas systems are widespread bacterial adaptive defence mechanisms that provide
protection against bacteriophages. In response, phages have evolved anti-CRISPR proteins …
protection against bacteriophages. In response, phages have evolved anti-CRISPR proteins …
The burden of cancer attributable to modifiable risk factors in Canada: Methods overview
Up-to-date estimates of current and projected future cancer burden attributable to various
exposures are essential for planning and implementing cancer prevention initiatives. The …
exposures are essential for planning and implementing cancer prevention initiatives. The …
Quadrivalent human papillomavirus vaccination in girls and the risk of autoimmune disorders: the Ontario Grade 8 HPV Vaccine Cohort Study
EY Liu, LM Smith, AK Ellis, H Whitaker, B Law… - Cmaj, 2018 - Can Med Assoc
BACKGROUND: Despite demonstrated effectiveness in real-world settings, concerns persist
regarding the safety of the quadrivalent human papillomavirus (HPV4) vaccine. We sought …
regarding the safety of the quadrivalent human papillomavirus (HPV4) vaccine. We sought …
[HTML][HTML] Factors associated with initiation and completion of the quadrivalent human papillomavirus vaccine series in an Ontario cohort of grade 8 girls
Background Although over a hundred million dollars have been invested in offering free
quadrivalent human papillomavirus (HPV) vaccination to young girls in Ontario, there …
quadrivalent human papillomavirus (HPV) vaccination to young girls in Ontario, there …