Background Following wider acceptance of 'the thrifty phenotype'hypothesis and the
convincing evidence that early‐life exposures can influence adult health even decades after …

Remarkable progress in the field of epigenetics has turned academic, medical and public
attention to the potential applications of these new advances in medicine and various fields …

A single cytosine–guanine dinucleotide (CpG) site within coagulation factor II (thrombin)
receptor-like 3 (F2RL3) was recently found to be hypomethylated in peripheral blood …

Background: Most biomarkers of exposure tend to have short half-lives. This includes
cotinine, a metabolite of nicotine widely used to assess smoke exposure. Cotinine is thus …

OBJECTIVE Meta-analyses of epidemiologic studies have suggested that metformin may
reduce cancer incidence, but randomized controlled trials did not support this hypothesis …

Background: In humans, low socioeconomic status (SES) across the life course is
associated with greater diurnal cortisol production, increased inflammatory activity and …

Objective This study aimed to construct a job exposure matrix (JEM) for risk of becoming
infected with the SARS-CoV-2 virus in an occupational setting. Methods Experts in …

Background Interest in the potential of DNA methylation in peripheral blood as a biomarker
of cancer risk is increasing. We aimed to assess whether epigenome-wide DNA methylation …

The use of omics represents a shift in approach for environmental epidemiology and
exposure science. In this article, the aspects of the use of omics that will require further …

Background Exposure to disinfection by-products (DBPs) in drinking water and chlorinated
swimming pools are associated with adverse health outcomes, but biological mechanisms …