To assess the value of promoting health through exercise, we review what is known about
the medical and medical care resource costs and benefits of exercise. Literatu re searches …

Adaptive designs (ADs) allow pre-planned changes to an ongoing trial without
compromising the validity of conclusions and it is essential to distinguish pre-planned from …

Objective: To assess the cost effectiveness of a community based exercise programme as a
population wide public health intervention for older adults. Design: Pragmatic, cluster …

Background: We have previously shown that in a randomized comparison of laparoscopic
(LC) versus small incision (SC) cholecystectomy, postoperative hospital stay is comparable …

Background. Nurses working in NHS Direct, the 24‐hour telephone advice line in England,
use computerized decision support software to recommend to callers the most appropriate …

Objective: There is no management regime for chronic fatigue syndrome (CFS) that has
been found to be universally beneficial and no treatment can be considered a “cure”[1] …

Injuries are an important cause of mortality and morbidity Although accidental injury rates
have been declining throughout the twentieth century in the UK, this pattern has been …

Objectives Health utility combines health related quality of life and mortality to produce a
generic outcome measure reflecting both morbidity and mortality. It has not been widely …

Objectives This study aimed to identify the perceptions of healthcare professionals regarding
the effectiveness and the impact of a new general practitioner-led (GP-led) walk-in centre in …

Editor—The review of climate change issues in the BMJ of 10 June was comprehensive. On
grounds of morality, the principle of contraction and convergence is unassailable. 1 In the …