Aging and insulin secretion

AM Chang, JB Halter - American Journal of Physiology …, 2003 - journals.physiology.org
Glucose tolerance progressively declines with age, and there is a high prevalence of type 2
diabetes and postchallenge hyperglycemia in the older population. Age-related glucose …

Insulin secretion in diabetes mellitus

MA Pfeifer, JB Halter, D Porte Jr - The American journal of medicine, 1981 - Elsevier
A brief review of the normal physiology of insulin secretion is given. The dual role of glucose
to directly stimulate insulin release and to potentiate insulin secretion to other islet regulators …

Diabetes and cardiovascular disease in older adults: current status and future directions

JB Halter, N Musi, F McFarland Horne, JP Crandall… - Diabetes, 2014 - Am Diabetes Assoc
The prevalence of diabetes increases with age, driven in part by an absolute increase in
incidence among adults aged 65 years and older. Individuals with diabetes are at higher risk …

[HTML][HTML] Diabetes in older adults

MS Kirkman, VJ Briscoe, N Clark, H Florez… - Diabetes …, 2012 - ncbi.nlm.nih.gov
More than 25% of the US population aged $65 years has diabetes (1), and the aging of the
overall population is a significant driver of the diabetes epidemic. Although the burden of …

[BOOK][B] Hazzard's geriatric medicine and gerontology

JB Halter - 2009 - academia.edu
Medicine is an ever-changing science. As new research and clinical experience broaden
our knowledge, changes in treatment and drug therapy are required. The authors and the …

[HTML][HTML] Workshop on HIV infection and aging: what is known and future research directions

RB Effros, CV Fletcher, K Gebo, JB Halter… - … diseases: an official …, 2008 - ncbi.nlm.nih.gov
Highly active antiretroviral treatment has resulted in dramatically increased life expectancy
among patients with HIV infection who are now aging while receiving treatment and are at …

Diminished B cell secretory capacity in patients with noninsulin-dependent diabetes mellitus.

WK Ward, DC Bolgiano, B McKnight… - The Journal of …, 1984 - Am Soc Clin Investig
In order to assess whether patients with noninsulin-dependent diabetes mellitus (NIDDM)
possess normal insulin secretory capacity, maximal B cell responsiveness to the potentiating …

[HTML][HTML] Diabetes in older adults: consensus report

MS Kirkman, VJ Briscoe, N Clark, H Florez… - Journal of the …, 2012 - ncbi.nlm.nih.gov
According to the most recent surveillance data, the prevalence of diabetes among US adults
over age 65 years varies from 22% to 33%, depending on the diagnostic criteria employed …

Treatment of diabetes in older adults: an Endocrine Society clinical practice guideline

D LeRoith, GJ Biessels, SS Braithwaite… - The Journal of …, 2019 - academic.oup.com
Objective The objective is to formulate clinical practice guidelines for the treatment of
diabetes in older adults. Conclusions Diabetes, particularly type 2, is becoming more …

Sympathetic nervous system activity in major depression: basal and desipramine-induced alterations in plasma norepinephrine kinetics

RC Veith, N Lewis, OA Linares… - Archives of general …, 1994 - jamanetwork.com
Background: To determine whether elevations of plasma norepinephrine (NE) in major
depression represent increased sympathetic nervous system (SNS) activity and to assess …