User profiles for "author:Jack Wilkinson"

Jack Wilkinson

Senior Lecturer, University of Manchester
Verified email at manchester.ac.uk
Cited by 5978

Prediction models for diagnosis and prognosis of covid-19: systematic review and critical appraisal

L Wynants, B Van Calster, GS Collins, RD Riley… - bmj, 2020 - bmj.com
Objective To review and appraise the validity and usefulness of published and preprint
reports of prediction models for prognosis of patients with covid-19, and for detecting people …

Short‐term and long‐term effects of tibolone in postmenopausal women

G Formoso, E Perrone, S Maltoni… - Cochrane Database …, 2016 - cochranelibrary.com
Background Tibolone is a synthetic steroid used for the treatment of menopausal symptoms,
on the basis of short‐term data suggesting its efficacy. We considered the balance between …

Individualised gonadotropin dose selection using markers of ovarian reserve for women undergoing in vitro fertilisation plus intracytoplasmic sperm injection (IVF/ICSI)

SF Lensen, J Wilkinson, JA Leijdekkers… - Cochrane Database …, 2018 - cochranelibrary.com
Background During a cycle of in vitro fertilisation plus intracytoplasmic sperm injection
(IVF/ICSI), women receive daily doses of gonadotropin follicle‐stimulating hormone (FSH) to …

A conserved tripeptide sorts proteins to peroxisomes.

SJ Gould, GA Keller, N Hosken, J Wilkinson… - The Journal of cell …, 1989 - rupress.org
The firefly luciferase protein contains a peroxisomal targeting signal at its extreme COOH
terminus (Gould et al., 1987). Site-directed mutagenesis of the luciferase gene reveals that …

An Ethylene-Inducible Component of Signal Transduction Encoded by Never-ripe

JQ Wilkinson, MB Lanahan, HC Yen, JJ Giovannoni… - Science, 1995 - science.org
The ripening-impaired tomato mutant Never-ripe (Nr) is insensitive to the plant hormone
ethylene. The gene that cosegregates with the Nr locus encodes a protein with homology to …

A dominant mutant receptor from Arabidopsis confers ethylene insensitivity in heterologous plants

JQ Wilkinson, MB Lanahan, DG Clark… - Nature …, 1997 - nature.com
Abstract Ethylene (C2H4) is a gaseous hormone that affects many aspects of plant growth
and development. Ethylene perception requires specific receptors and a signal transduction …

Enhanced Levels of the Aroma and Flavor Compound S-Linalool by Metabolic Engineering of the Terpenoid Pathway in Tomato Fruits

E Lewinsohn, F Schalechet, J Wilkinson… - Plant …, 2001 - academic.oup.com
The aromas of fruits, vegetables, and flowers are mixtures of volatile metabolites, often
present in parts per billion levels or less. We show here that tomato (Lycopersicon …

Identification and characterization of a chlorate-resistant mutant of Arabidopsis thaliana with mutations in both nitrate reductase structural genes NIA1 and NIA2

JQ Wilkinson, NM Crawford - Molecular and General Genetics MGG, 1993 - Springer
Mutant plants defective in the assimilation of nitrate can be selected by their resistance to the
herbicide chlorate. In Arabidopsis thaliana, mutations at any one of nine distinct loci confer …

[HTML][HTML] Time to reality check the promises of machine learning-powered precision medicine

J Wilkinson, KF Arnold, EJ Murray… - The Lancet Digital …, 2020 - thelancet.com
Machine learning methods, combined with large electronic health databases, could enable
a personalised approach to medicine through improved diagnosis and prediction of …

[HTML][HTML] A randomized trial of endometrial scratching before in vitro fertilization

S Lensen, D Osavlyuk, S Armstrong… - … England Journal of …, 2019 - Mass Medical Soc
Background Endometrial scratching (with the use of a pipelle biopsy) is a technique
proposed to facilitate embryo implantation and increase the probability of pregnancy in …