Age-associated cognitive decline
Introduction Age-associated cognitive decline—or normal (non-pathological, normative,
usual) cognitive ageing—is an important human experience which differs in extent between …
usual) cognitive ageing—is an important human experience which differs in extent between …
[HTML][HTML] The Lothian Birth Cohort 1936: a study to examine influences on cognitive ageing from age 11 to age 70 and beyond
Background Cognitive ageing is a major burden for society and a major influence in
lowering people's independence and quality of life. It is the most feared aspect of ageing …
lowering people's independence and quality of life. It is the most feared aspect of ageing …
Target risk factors for dementia prevention: a systematic review and Delphi consensus study on the evidence from observational studies
K Deckers, MPJ van Boxtel… - … journal of geriatric …, 2015 - Wiley Online Library
Objective Dementia has a multifactorial etiology, but the importance of individual health and
lifestyle related risk factors is often uncertain or based on few studies. The goal of this paper …
lifestyle related risk factors is often uncertain or based on few studies. The goal of this paper …
[HTML][HTML] DNA methylation age of blood predicts all-cause mortality in later life
Background DNA methylation levels change with age. Recent studies have identified
biomarkers of chronological age based on DNA methylation levels. It is not yet known …
biomarkers of chronological age based on DNA methylation levels. It is not yet known …
Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence
Intelligence is highly heritable and a major determinant of human health and well-being.
Recent genome-wide meta-analyses have identified 24 genomic loci linked to variation in …
Recent genome-wide meta-analyses have identified 24 genomic loci linked to variation in …
[HTML][HTML] Grip strength across the life course: normative data from twelve British studies
Introduction Epidemiological studies have shown that weaker grip strength in later life is
associated with disability, morbidity, and mortality. Grip strength is a key component of the …
associated with disability, morbidity, and mortality. Grip strength is a key component of the …
The impact of childhood intelligence on later life: following up the Scottish mental surveys of 1932 and 1947.
IJ Deary, MC Whiteman, JM Starr… - Journal of personality …, 2004 - psycnet.apa.org
Abstract The Scottish Mental Surveys of 1932 and 1947 collected valid IQ-type test scores
for almost everyone born in 1921 and 1936 and attending school on June 1, 1932 (N …
for almost everyone born in 1921 and 1936 and attending school on June 1, 1932 (N …
Epigenetic signatures of cigarette smoking
Background—DNA methylation leaves a long-term signature of smoking exposure and is
one potential mechanism by which tobacco exposure predisposes to adverse health …
one potential mechanism by which tobacco exposure predisposes to adverse health …
Genome-wide association studies establish that human intelligence is highly heritable and polygenic
General intelligence is an important human quantitative trait that accounts for much of the
variation in diverse cognitive abilities. Individual differences in intelligence are strongly …
variation in diverse cognitive abilities. Individual differences in intelligence are strongly …
Identification of common variants associated with human hippocampal and intracranial volumes
Identifying genetic variants influencing human brain structures may reveal new biological
mechanisms underlying cognition and neuropsychiatric illness. The volume of the …
mechanisms underlying cognition and neuropsychiatric illness. The volume of the …