User profiles for "author:J Lahti"

Jari Lahti

Professor, Department of Psychology and Logopedics, University of Helsinki
Verified email at helsinki.fi
Cited by 26911

Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption

…, JM Vink, JH Zhao, G Burlutsky, J Lahti… - Molecular …, 2015 - nature.com
Coffee, a major dietary source of caffeine, is among the most widely consumed beverages in
the world and has received considerable attention regarding health risks and benefits. We …

Role of CDK/cyclin complexes in transcription and RNA splicing

P Loyer, JH Trembley, R Katona, VJ Kidd, JM Lahti - Cellular signalling, 2005 - Elsevier
The production of mRNAs in all living organisms is an extremely complex process that
includes multiple catalytic activities such as transcription, capping, splicing, polyadenylation …

The connections between neural crest development and neuroblastoma

M Jiang, J Stanke, JM Lahti - Current topics in developmental biology, 2011 - Elsevier
Neuroblastoma (NB), the most common extracranial solid tumor in childhood, is an
extremely heterogeneous disease both biologically and clinically. Although significant …

Genome-wide association study identifies 74 loci associated with educational attainment

…, K Kaasik, IP Kalafati, R Karlsson, A Kong, J Lahti… - Nature, 2016 - nature.com
Educational attainment is strongly influenced by social and other environmental factors, but
genetic factors are estimated to account for at least 20% of the variation across individuals 1 …

Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence

…, MC Keller, E Knowles, D Koltai, B Konte, J Lahti… - Nature …, 2018 - nature.com
Intelligence is highly heritable and a major determinant of human health and well-being.
Recent genome-wide meta-analyses have identified 24 genomic loci linked to variation in …

Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

…, R Karlsson, SW van der Laan, KH Ladwig, J Lahti… - Nature …, 2016 - nature.com
Very few genetic variants have been associated with depression and neuroticism, likely
because of limitations on sample size in previous studies. Subjective well-being, a …

GWAS of 126,559 individuals identifies genetic variants associated with educational attainment

…, I Kolcic, K Kristiansson, Z Kutalik, J Lahti… - science, 2013 - science.org
A genome-wide association study (GWAS) of educational attainment was conducted in a
discovery sample of 101,069 individuals and a replication sample of 25,490. Three …

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

…, T Johnson, S Kanoni, C Ladenvall, V Lagou, J Lahti… - Nature …, 2012 - nature.com
Recent genome-wide association studies have described many loci implicated in type 2
diabetes (T2D) pathophysiology and β-cell dysfunction but have contributed little to the …

Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN

T Teitz, T Wei, MB Valentine, EF Vanin, J Grenet… - Nature medicine, 2000 - nature.com
Caspase 8 is a cysteine protease regulated in both a death-receptor-dependent and-
independent manner during apoptosis. Here, we report that the gene for caspase 8 is …

[HTML][HTML] Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

…, MA Ikram, R Karlsson, E Knowles, J Lahti… - Nature …, 2018 - nature.com
General cognitive function is a prominent and relatively stable human trait that is associated
with many important life outcomes. We combine cognitive and genetic data from the …