Background The rising prevalence of overweight and obesity places a financial burden on
health services and on the wider economy. Health service and societal costs of overweight …

Background Alcohol is a leading cause of global suffering. Europe reports the uppermost
volume of alcohol consumption in the world, with Ireland and the United Kingdom reporting …

Objective To evaluate the effectiveness of workplace dietary modification interventions alone
or in combination with nutrition education on employees' dietary behaviour, health status …

Background Although statins reduce coronary and cerebrovascular morbidity and mortality
in middle-aged individuals, their efficacy and safety in elderly people is not fully established …

Moderate hyperhomocysteinaemia is common in the general population and has been
linked with cardiovascular disease. However, there are no data from prospective, population …

Objective: To determine the risk factors for non-insulin dependent diabetes in a cohort
representative of middle aged British men. Design: Prospective study. Subjects and setting …

The PROspective Study of Pravastatin in the Elderly at Risk (PROSPER) is a randomized,
double-blind, placebo-controlled trial designed to test the hypothesis that treatment with …

OBJECTIVE—To examine the effects of cigarette smoking, giving up smoking, and primary
or secondary pipe or cigar smoking on the risk of type 2 diabetes. RESEARCH DESIGN …

OBJECTIVE Serum γ-glutamyltransferase (GGT) levels are raised inobese individuals, and a
particularly strong association with central obesity has been described. We hypothesized …

Background and Purpose Elevated serum creatinine has been associated with increased
mortality in hypertensive persons, the elderly, and patients with myocardial infarction or …