Ageing is accompanied by 2–4-fold increases in plasma/serum levels of inflammatory
mediators such as cytokines and acute phase proteins. A wide range of factors seems to …

Aging is associated with increased inflammatory activity reflected by increased circulating
levels of TNF-α, IL-6, cytokine antagonists and acute phase proteins in vivo. Epidemiologic …

Studies have demonstrated that circulating levels of plasma cytokines are influenced greatly
by age and that chronic elevated levels of certain cytokines are associated with chronic …

It has been recognized for some time that cardiovascular disease and type 2 diabetes are, to
a major extent, inflammatory disorders associated with an environment characterized by a …

Background. Inflammatory mechanisms and immune activation have been hypothesized to
play a role in the pathogenesis of age-associated diseases such as dementia and …

The purpose of the current study was to test the hypothesis that an altered fat distribution in
elderly healthy subjects and in patients with type-2 diabetes contributes to high circulating …

Brain-derived neurotrophic factor (BDNF) is one of the key molecules modulating brain
plasticity. While low circulating levels of BDNF have been suggested to predispose to …

BACKGROUND: Aging is accompanied by low-grade inflammation. Tumor necrosis factor
(TNF) α initiates the cytokine cascade, and high levels are associated with dementia and …

Ageing is associated with low-grade inflammation and markers such as IL-6 possess
prognostic value. Tumour necrosis-alpha (TNF-α) initiates the inflammatory cascade and …

Brain‐derived neurotrophic factor (BDNF) has been shown to regulate neuronal
development and plasticity and plays a role in learning and memory. Moreover, it is well …