Summary The European Association for Neuro-Oncology guideline provides
recommendations for the clinical care of adult patients with astrocytic and oligodendroglial …

There are over 120 types of brain tumor and approximately 45% of primary brain tumors are
gliomas, of which glioblastoma multiforme (GBM) is the most common and aggressive with a …

Glioblastoma multiforme (GBM), a grade IV astrocytoma, is the most common and deadly
type of primary malignant brain tumor, with a patient's median survival rate ranging from 15 …

In vitro models of the blood–brain barrier (B-BB) generally utilise murine or porcine brain
endothelium and rat astrocytes which are commonly grown in foetal calf serum …

B7-H4 protein is expressed on the surface of a variety of immune cells and functions as a
negative regulator of T cell responses. We independently identified B7-H4 (DD-O110) …

A large number (33) of human Fab fragments reacting with HIV-1 surface glycoprotein
gp120 have been generated by selection from a combinatorial IgGlκ library displayed on the …

Purpose: This study was designed to investigate the expression of B7-H4 protein, a member
of the B7 family that is involved in the regulation of antigen-specific immune responses, in …

Human gliomas are characterized by their invasion of normal brain structures irrespective of
their grade of malignancy. Factors involved in the control of this invasive behavior are poorly …

Factors involved in the control of the biological properties of gliomas, the major form of brain
tumour in man, are poorly documented. We investigated the role of transforming growth …

Our aim was to evaluate the clinical effectiveness of chemotherapy treatments currently
licensed in Europe and recommended by the National Institute for Health and Care …