User profiles for "author:Frederick S vom Saal"

Frederick S. vom Saal

Curators' Distinguished Professor Emeritus of Biology, University of Missouri
Verified email at missouri.edu
Cited by 47043

Plastics, the environment and human health: current consensus and future trends

RC Thompson, CJ Moore… - … transactions of the …, 2009 - royalsocietypublishing.org
Plastics have transformed everyday life; usage is increasing and annual production is likely
to exceed 300 million tonnes by 2010. In this concluding paper to the Theme Issue on …

Developmental effects of endocrine-disrupting chemicals in wildlife and humans.

T Colborn, FS Vom Saal, AM Soto - Environmental health …, 1993 - ehp.niehs.nih.gov
Large numbers and large quantities of endocrine-disrupting chemicals have been released
into the environment since World War II. Many of these chemicals can disturb development …

Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses

LN Vandenberg, T Colborn, TB Hayes… - Endocrine …, 2012 - academic.oup.com
For decades, studies of endocrine-disrupting chemicals (EDCs) have challenged traditional
concepts in toxicology, in particular the dogma of “the dose makes the poison,” because …

In vivo effects of bisphenol A in laboratory rodent studies

CA Richter, LS Birnbaum, F Farabollini… - Reproductive …, 2007 - Elsevier
Concern is mounting regarding the human health and environmental effects of bisphenol A
(BPA), a high-production-volume chemical used in synthesis of plastics. We have reviewed …

Our plastic age

RC Thompson, SH Swan… - … Transactions of the …, 2009 - royalsocietypublishing.org
Within the last few decades, plastics have revolutionized our daily lives. Globally we use in
excess of 260 million tonnes of plastic per annum, accounting for approximately 8 per cent of …

Large effects from small exposures. III. Endocrine mechanisms mediating effects of bisphenol A at levels of human exposure

WV Welshons, SC Nagel, FS vom Saal - Endocrinology, 2006 - academic.oup.com
Over 6 billion pounds per year of the estrogenic monomer bisphenol A (BPA) are used to
manufacture polycarbonate plastic products, in resins lining metal cans, in dental sealants …

An extensive new literature concerning low-dose effects of bisphenol A shows the need for a new risk assessment

FS Vom Saal, C Hughes - Environmental health perspectives, 2005 - ehp.niehs.nih.gov
Bisphenol A (BPA) is the monomer used to manufacture polycarbonate plastic, the resin
lining of cans, and other products, with global capacity in excess of 6.4 billion lb/year …

Chapel Hill bisphenol A expert panel consensus statement: integration of mechanisms, effects in animals and potential to impact human health at current levels of …

FS Vom Saal, BT Akingbemi, SM Belcher… - Reproductive …, 2007 - Elsevier
This document is a summary statement of the outcome from the meeting:“Bisphenol A: An
Examination of the Relevance of Ecological, In vitro and Laboratory Animal Studies for …

A physiologically based approach to the study of bisphenol A and other estrogenic chemicals on the size of reproductive organs, daily sperm production, and behavior

FS Vom Saal, PS Cooke… - Toxicology and …, 1998 - journals.sagepub.com
Two chemicals previously shown to have estrogenic activity, bisphenol A and octylphenol,
were examined for their effects on accessory reproductive organs and daily sperm …

Relative binding affinity-serum modified access (RBA-SMA) assay predicts the relative in vivo bioactivity of the xenoestrogens bisphenol A and octylphenol.

SC Nagel, FS vom Saal, KA Thayer… - Environmental …, 1997 - ehp.niehs.nih.gov
We have developed a relative binding affinity-serum modified access (RBA-SMA) assay to
determine the effect of serum on the access of xenoestrogens to estrogen receptors within …