Mendelian randomization
Mendelian randomization (MR) is a term that applies to the use of genetic variation to
address causal questions about how modifiable exposures influence different outcomes …
address causal questions about how modifiable exposures influence different outcomes …
Multivariable Mendelian randomization and mediation
E Sanderson - Cold Spring Harbor perspectives …, 2021 - perspectivesinmedicine.cshlp.org
Mendelian randomization (MR) is the use of genetic variants associated with an exposure to
estimate the causal effect of that exposure on an outcome. Mediation analysis is the method …
estimate the causal effect of that exposure on an outcome. Mediation analysis is the method …
Novel ecosystems: theoretical and management aspects of the new ecological world order
We explore the issues relevant to those types of ecosystems containing new combinations of
species that arise through human action, environmental change, and the impacts of the …
species that arise through human action, environmental change, and the impacts of the …
The human footprint and the last of the wild: the human footprint is a global map of human influence on the land surface, which suggests that human beings are …
Articles sions of 6 billion people add up to a global phenomenon in a way unique to our
time. What we need is a way to understand this influence that is global in extent and yet easy …
time. What we need is a way to understand this influence that is global in extent and yet easy …
[HTML][HTML] Sixteen years of change in the global terrestrial human footprint and implications for biodiversity conservation
Human pressures on the environment are changing spatially and temporally, with profound
implications for the planet's biodiversity and human economies. Here we use recently …
implications for the planet's biodiversity and human economies. Here we use recently …
Bone marrow-derived cells as progenitors of lung alveolar epithelium
DN Kotton, BY Ma, WV Cardoso, EA Sanderson… - 2001 - journals.biologists.com
We assessed the capacity of plastic-adherent cultured bone marrow cells to serve as
precursors of differentiated parenchymal cells of the lung. By intravenously delivering lacZ …
precursors of differentiated parenchymal cells of the lung. By intravenously delivering lacZ …
[HTML][HTML] A weak instrument F-test in linear IV models with multiple endogenous variables
E Sanderson, F Windmeijer - Journal of econometrics, 2016 - Elsevier
We consider testing for weak instruments in a model with multiple endogenous variables.
Unlike Stock and Yogo (2005), who considered a weak instruments problem where the rank …
Unlike Stock and Yogo (2005), who considered a weak instruments problem where the rank …
[HTML][HTML] Global terrestrial Human Footprint maps for 1993 and 2009
Remotely-sensed and bottom-up survey information were compiled on eight variables
measuring the direct and indirect human pressures on the environment globally in 1993 and …
measuring the direct and indirect human pressures on the environment globally in 1993 and …
Planning to save a species: the jaguar as a model
EW Sanderson, KH Redford… - Conservation …, 2002 - Wiley Online Library
International conservation planning at the end of the twentieth century is dominated by
coarse‐filter, supra‐organismal approaches to conservation that may be insufficient to …
coarse‐filter, supra‐organismal approaches to conservation that may be insufficient to …
An examination of multivariable Mendelian randomization in the single-sample and two-sample summary data settings
E Sanderson, G Davey Smith… - International journal …, 2019 - academic.oup.com
Background Mendelian randomization (MR) is a powerful tool in epidemiology that can be
used to estimate the causal effect of an exposure on an outcome in the presence of …
used to estimate the causal effect of an exposure on an outcome in the presence of …