International consensus criteria for the diagnosis of Raynaud's phenomenon

E Maverakis, F Patel, DG Kronenberg, L Chung… - Journal of …, 2014 - Elsevier
Vasoconstriction accompanied by changes in skin color is a normal physiologic response to
cold. The distinction between this normal physiology and Raynaud's phenomenon (RP) has …

Characterizing the quantitative genetic contribution to rheumatoid arthritis using data from twins

AJ MacGregor, H Snieder, AS Rigby… - … : Official Journal of …, 2000 - Wiley Online Library
Objective Twin concordance data for rheumatoid arthritis (RA) on their own provide only
limited insight into the relative genetic and environmental contribution to the disease. We …

Cigarette smoking increases the risk of rheumatoid arthritis: results from a nationwide study of disease‐discordant twins

AJ Silman, J Newman, AJ Macgregor - Arthritis & Rheumatism, 1996 - Wiley Online Library
Objective. To test the hypothesis that cigarette smoking is associated with susceptibility to
rheumatoid arthritis (RA) by comparing smoking history between twins with RA and their …

Structural, psychological, and genetic influences on low back and neck pain: a study of adult female twins

AJ MacGregor, T Andrew, PN Sambrook… - Arthritis Care & …, 2004 - Wiley Online Library
Objective To assess genetic and environmental influences on low back and neck pain in a
classic twin design and to examine the extent to which these are explained by structural …

The association of body mass index and osteoarthritis of the knee joint: an examination of genetic and environmental influences

NJ Manek, D Hart, TD Spector… - Arthritis & Rheumatism …, 2003 - Wiley Online Library
Objective To examine the genetic and environmental influences on the known association
between body mass index (BMI) and knee osteoarthritis (OA), using adult twin data. Methods …

Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis

K Ishigaki, S Sakaue, C Terao, Y Luo, K Sonehara… - Nature …, 2022 - nature.com
Rheumatoid arthritis (RA) is a highly heritable complex disease with unknown etiology. Multi-
ancestry genetic research of RA promises to improve power to detect genetic signals, fine …

The genetic contribution to radiographic hip osteoarthritis in women: results of a classic twin study

AJ MacGregor, L Antoniades, M Matson… - … : Official Journal of …, 2000 - Wiley Online Library
Objective To assess the genetic contribution to radiographic hip osteoarthritis (OA) by
measuring the distribution of disease features in monozygotic (MZ) and dizygotic (DZ) twins …

Schmorl's nodes: common, highly heritable, and related to lumbar disc disease

FMK Williams, NJ Manek, PN Sambrook… - Arthritis Care & …, 2007 - Wiley Online Library
Objective Schmorl's nodes (SN) are common, but little is known of their relationship with
degenerative change and back pain or genetic and environmental factors influencing their …

[HTML][HTML] Hippurate as a metabolomic marker of gut microbiome diversity: Modulation by diet and relationship to metabolic syndrome

T Pallister, MA Jackson, TC Martin, J Zierer… - Scientific reports, 2017 - nature.com
Reduced gut microbiome diversity is associated with multiple disorders including metabolic
syndrome (MetS) features, though metabolomic markers have not been investigated. Our …

The genetic epidemiology of joint hypermobility: a population study of female twins

AJ Hakim, LF Cherkas, R Grahame… - … : Official Journal of …, 2004 - Wiley Online Library
Objective To estimate the genetic influence on joint hypermobility in an unselected
population using a classic twin study design. Methods A self‐report questionnaire on joint …