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Page 1
An RNA modification with remarkable resistance to RNase A.
Ghidini A, Ander C, Winqvist A, Strömberg R. Ghidini A, et al. Among authors: winqvist a. Chem Commun (Camb). 2013 Oct 11;49(79):9036-8. doi: 10.1039/c3cc44621b. Chem Commun (Camb). 2013. PMID: 23982594
The design, synthesis, and antiviral activity of monofluoro and difluoro analogues of 4'-azidocytidine against hepatitis C virus replication: the discovery of 4'-azido-2'-deoxy-2'-fluorocytidine and 4'-azido-2'-dideoxy-2',2'-difluorocytidine.
Smith DB, Kalayanov G, Sund C, Winqvist A, Maltseva T, Leveque VJ, Rajyaguru S, Le Pogam S, Najera I, Benkestock K, Zhou XX, Kaiser AC, Maag H, Cammack N, Martin JA, Swallow S, Johansson NG, Klumpp K, Smith M. Smith DB, et al. Among authors: winqvist a. J Med Chem. 2009 May 14;52(9):2971-8. doi: 10.1021/jm801595c. J Med Chem. 2009. PMID: 19341305
Discovery of 4'-azido-2'-deoxy-2'-C-methyl cytidine and prodrugs thereof: a potent inhibitor of Hepatitis C virus replication.
Nilsson M, Kalayanov G, Winqvist A, Pinho P, Sund C, Zhou XX, Wähling H, Belfrage AK, Pelcman M, Agback T, Benckestock K, Wikström K, Boothee M, Lindqvist A, Rydegård C, Jonckers TH, Vandyck K, Raboisson P, Lin TI, Lachau-Durand S, de Kock H, Smith DB, Martin JA, Klumpp K, Simmen K, Vrang L, Terelius Y, Samuelsson B, Rosenquist S, Johansson NG. Nilsson M, et al. Among authors: winqvist a. Bioorg Med Chem Lett. 2012 May 1;22(9):3265-8. doi: 10.1016/j.bmcl.2012.03.021. Epub 2012 Mar 16. Bioorg Med Chem Lett. 2012. PMID: 22472694
The design, synthesis, and antiviral activity of 4'-azidocytidine analogues against hepatitis C virus replication: the discovery of 4'-azidoarabinocytidine.
Smith DB, Kalayanov G, Sund C, Winqvist A, Pinho P, Maltseva T, Morisson V, Leveque V, Rajyaguru S, Le Pogam S, Najera I, Benkestock K, Zhou XX, Maag H, Cammack N, Martin JA, Swallow S, Johansson NG, Klumpp K, Smith M. Smith DB, et al. Among authors: winqvist a. J Med Chem. 2009 Jan 8;52(1):219-23. doi: 10.1021/jm800981y. J Med Chem. 2009. PMID: 19055482
Studies on the stability of dinucleoside H-phosphonates.
Heinonen P, Winqvist A, Sanghvi Y, Strömberg R. Heinonen P, et al. Among authors: winqvist a. Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):1387-9. doi: 10.1081/NCN-120022992. Nucleosides Nucleotides Nucleic Acids. 2003. PMID: 14565425