Bisphenol-A and phthalates contamination of urine samples by catheters in the Elfe pilot study: implications for large-scale biomonitoring studies

Environ Res. 2011 Aug;111(6):761-4. doi: 10.1016/j.envres.2011.05.018.

Abstract

Exposure to phthalates and Bisphenol A could cause developmental and reproductive toxicity. This study provides a first assessment of these exposures for more than 250 French pregnant women. The median concentrations of total and free Bisphenol A in urine were similar to those in other studies except the highest concentrations (5% of women had total and free Bisphenol A >50μg/L). Our study highlights high levels of Di-(2-ethylhexyl)-phthalate metabolites in pregnant women, suggesting recent exposure, probably in hospital. Differences between types of delivery (caesarean vs. natural) support this hypothesis. This is a significant implication for large-scale biomonitoring studies among this population.

Publication types

  • Validation Study

MeSH terms

  • Benzhydryl Compounds
  • Catheters
  • Environmental Monitoring / methods*
  • Environmental Pollutants / urine*
  • Female
  • France
  • Humans
  • Phenols / urine*
  • Phthalic Acids / urine*
  • Pilot Projects
  • Pregnancy
  • Urine / chemistry*

Substances

  • Benzhydryl Compounds
  • Environmental Pollutants
  • Phenols
  • Phthalic Acids
  • phthalic acid
  • bisphenol A