Abstract
Epidemiologic evidence suggests that cancer incidence is associated with diabetes as well as certain diabetes risk factors and treatments. This consensus statement of experts assembled jointly by the American Diabetes Association and the American Cancer Society reviews the state of science concerning 1) the association between diabetes and cancer incidence or prognosis; 2) risk factors common to both diabetes and cancer; 3) possible biologic links between diabetes and cancer risk; and 4) whether diabetes treatments influence the risk of cancer or cancer prognosis. In addition, key unanswered questions for future research are posed.
(c) 2010 American Cancer Society, Inc.
Publication types
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Consensus Development Conference
MeSH terms
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Age Factors
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Alcohol Drinking
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Body Mass Index
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Cytokines / metabolism
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Diabetes Complications*
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Diabetes Mellitus / drug therapy
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Diet
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Estrogens / blood
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Humans
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Hyperglycemia / complications
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Hyperinsulinism / complications
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Hypoglycemic Agents / administration & dosage
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Hypoglycemic Agents / adverse effects
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Incretins / administration & dosage
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Incretins / adverse effects
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Insulin / administration & dosage
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Insulin / adverse effects
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Insulin / analogs & derivatives
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Metformin / administration & dosage
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Metformin / adverse effects
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Motor Activity
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Neoplasms / complications*
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Neoplasms / etiology*
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Neoplasms / metabolism
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Overweight
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Racial Groups
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Receptor, IGF Type 1 / metabolism
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Receptor, Insulin / metabolism
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Risk Factors
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Sex Factors
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Smoking / adverse effects
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Sulfonylurea Compounds / administration & dosage
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Sulfonylurea Compounds / adverse effects
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Testosterone / blood
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Thiazolidinediones / administration & dosage
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Thiazolidinediones / adverse effects
Substances
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Cytokines
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Estrogens
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Hypoglycemic Agents
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Incretins
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Insulin
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Sulfonylurea Compounds
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Thiazolidinediones
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Testosterone
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Metformin
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Receptor, IGF Type 1
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Receptor, Insulin