Original InvestigationPathogenesis and Treatment of Kidney DiseasePrevalence and Awareness of CKD Among African Americans: The Jackson Heart Study
Section snippets
Study Design, Participants, and Measurements
The JHS is a single-site longitudinal population-based study designed to prospectively explore the determinants (both individual and environmental) and genetic linkages that influence the development of CVD in African Americans. The sample consists of 5,302 women and men selected between 2000 and 2004 from a tricounty area of Mississippi: Hinds, Madison, and Rankin counties. The rationale for the study stems from the large disparity in cardiovascular mortality between Mississippi African
Descriptive Data
After excluding participants with restricted consent (n = 23) or without sufficient serum (n = 56) or urine data (n = 1,792) to determine CKD status, 3,431 participants (2,154 women and 1,277 men) were used in these analyses. Of the included participants, 1,015 had 24-hour and 2,255 had spot urine collections; an additional 161 participants with missing urine data were classified as having CKD because of low eGFR or being on dialysis therapy. Table 1 lists baseline characteristics of the JHS by
Discussion
The findings of this cross-sectional cohort of African American adults enrolled in the JHS further confirm the increasing national epidemic of CKD, particularly in non-Hispanic African Americans, with prevalence estimates similar to the most current national estimates of 16.8% for the entire population reported by the Centers for Disease Control and Prevention from analyses of the 1999 to 2004 NHANES data.4 Older participants (≥60 years) in both the NHANES (39.4%) and JHS (31.7%) had a greater
Acknowledgements
Support: This study was funded by the National Heart, Lung, and Blood Institute, National Institutes of Health.
Financial Disclosure: None.
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