Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Paper
  • Published:

Anthropometric indexes in the prediction of type 2 diabetes mellitus, hypertension and dyslipidaemia in a Mexican population

Abstract

OBJECTIVE: To determine values of simple anthropometric measurements which are associated with the presence of type 2 diabetes mellitus, hypertension and dyslipidaemia and to assess anthropometric cut-off values for predicting the likelihood of these chronic conditions in a Mexican population.

DESIGN AND SETTING: The data were obtained from PRIT (Prevalence of Cardiovascular Risk Factors in General Hospital Workers) surveys from 1994 to 2000 adjusted to the structure of the overall Mexican population.

SUBJECTS: A total of 2426 men and 5939 women aged 38.99±7.11 and 39.11±14.25 y, respectively.

MEASUREMENTS: The optimal sensitivity and specificity of using various cut-off values of BMI (body mass index), WHR (waist-to-hip ratio), WC (waist circumference) and WTH (waist-to-height ratio) to predict type 2 diabetes mellitus (DM), hypertension (HT), or dyslipidaemia were examined by receiver operating characteristic curve (ROC) analysis. The likelihood ratios for having diabetes, hypertension and dyslipidaemia in subjects with various cut-off values of BMI, WHR, WC and WTH were calculated. Multiple step-wise logistic regression analysis was used to examine the independent relationship between the anthropometric indexes, age and smoking, and the odds ratio of having chronic conditions.

RESULTS: The BMI cut-off to predict DM, HT, or dyslipidaemia varied from 25.2 to 26.6 kg/m2 in both men and women. The optimal WC cut-offs were 90 cm in men and 85 cm in women. The WHR cut-off was about 0.90 in men and 0.85 in women, and the optimal WTH cut-off was 52.5 in men and varied from 53 to 53.5 in women. The cut-off levels for WC, WHR and WTH corresponded to the inflexion points in the likelihood ratio graphs. In the case of BMI likelihood ratio graphs, we found a significant increase in the risk for chronic conditions from 22 to 23 BMI levels in both genders. Logistic regression analyses disclosed that only BMI and age were included in all the models as well as the influence of smoking in DM and dyslipidaemia in men.

CONCLUSION: Although these results may not be readily applied to the rest of the Mexican population or to other Hispanic populations, they point to the necessity of similar studies with large randomized samples to find the cut-off levels for chronic conditions in different populations.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1
Figure 2

Similar content being viewed by others

References

  1. Pi-Sunyer FX . Medical hazards of obesity Ann Intern Med 1993 119 (7 Pt 2): 655–660.

    Article  CAS  Google Scholar 

  2. Higgins M, Kannel W, Garrison R, Pinsky J, Stokes J . Hazards of obesity—the Framingham experience Acta Med Scand 1988 723 (Suppl): S23–S36.

    Google Scholar 

  3. Must A, Spadano J, Coakley EH, Field AE, Colditz G, Dietz WH . The disease burden associated with overweight and obesity JAMA 1999 282: 1523–1529.

    Article  CAS  Google Scholar 

  4. World Health Organization . Obesity. Preventing and managing the global epidemic Report of a WHO Consultation on Obesity, Geneva, 3–5 June World Health Organization: Geneva 1998

    Google Scholar 

  5. US National Institutes of Health . Clinical guidelines for the identification, evaluation, and treatment of overweight and obesity in adults National Institutes of Health: Bethesda, MD 1998

    Google Scholar 

  6. Okosun IS, Liao Y, Rotimi CN, Choi S, Cooper RS . Predictive values of waist circumference for dyslipidaemia, type 2 diabetes and hypertension in overweight White, Black, and Hispanic American adults J Clin Epidemiol 2000 53: 401–408.

    Article  CAS  Google Scholar 

  7. Molarius A, Seidell JC, Sans S, Tuomilehto J, Kuulasmaa K . Varying sensitivity of waist action levels to identify subjects with overweight or obesity in 19 populations of the WHO MONICA Project J Clin Epidemiol 1999 52: 1213–1224.

    Article  CAS  Google Scholar 

  8. Okosun IS, Rotimi CN, Forrester TE, Fraser H, Osotimehin B, Muna WF, Cooper RS . Predictive value of abdominal obesity cutoff points for hypertension in blacks from west African and Caribbean island nations Int J Obes Relat Metab Disord 2000 24: 180–186.

    Article  CAS  Google Scholar 

  9. Ko GT, Chan JC, Cockram CS, Woo J . Prediction of hypertension, diabetes, dyslipidaemia or albuminuria using simple anthropometric indexes in Hong Kong Chinese Int J Obes Relat Metab Disord 1999 23: 1136–1142.

    Article  CAS  Google Scholar 

  10. Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus Diabetes Care 1997 20: 1183–1197.

  11. American Heart Association . Science advisory guide to primary prevention of cardiovascular diseases: a statement for healthcare professionals from the Task Force on Risk Reduction Circulation 1997 95: 2329–2331.

    Article  Google Scholar 

  12. Summary of the second report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult treatment Panel II) JAMA 1993 269: 3015–3023.

  13. www.inegi.gob.mx/

  14. Van der Schouw YT, Verbeek AL, Ruijs JH . ROC curves for the initial assessment of new diagnostic tests Family Pract 1992 9: 506–511.

    Article  CAS  Google Scholar 

  15. Altman DG . Diagnostic tests. In: Altman DG, Machin D, Bryant TN, Gardner MJ (eds) Statistics with confidence 2nd edn BMJ Books: London 2000 105–119.

    Google Scholar 

  16. Han TS, van Leer EM, Seidell JC, Lean ME . Waist circumference as a screening tool for cardiovascular risk factors: evaluation of receiver operating characteristics (ROC) Obes Res 1996 4: 533–547.

    Article  CAS  Google Scholar 

  17. Simel DL, Samsa GP, Matchar DB . Likelihood ratios with confidence: sample size estimation for diagnostic test studies J Clin Epidemiol 1991 44: 763–770.

    Article  CAS  Google Scholar 

  18. Fanghänel-Salmón G, Sánchez-Reyes L, Arellano-Montaño S, Váldez-Liaz E, Chavira López J, Rascón-Pacheco RA . Prevalencia de factores de Riesgo de enfermedad coronoaria en trabajadores del Hospital General de México Salud Pública (Mex) 1997 39: 427–432.

    Article  Google Scholar 

  19. Fanghänel G, Sánchez-Reyes L, Berber A, Gómez-Santos R . Evolution of the prevalence of obesity in the workers of a General Hospital in Mexico Obes Res 2001 9: 268–273.

    Article  Google Scholar 

  20. Arroyo P, Loria A, Fernández V, Flegal KM, Kuri-Morales P, Olaiz G, Tapia-Conyer R . Prevalence of pre-obesity and obesity in urban adult Mexicans in comparison with other large surveys Obes Res 2000 8: 179–185.

    Article  CAS  Google Scholar 

  21. Encuesta Nacional de Enfermedades Crónicas . Epidemiología SSA 1993

  22. Flegal KM, Carroll MD, Kuczmarski RJ, Johnson CL . Overweight and obesity in the United States: prevalence and trends, 1960–1994 Int J Obes Relat Metab Disord 1998 22: 39–47.

    Article  CAS  Google Scholar 

  23. Harris MI, Flegal KM, Cowie CC, Eberhardt MS, Goldstein DE, Little RR, Wiedmeyer HM, Byrd-Holt DD . Prevalence of diabetes, impaired fasting glucose, and impaired glucose tolerance in U.S. adults. Third National Health and Nutrition Examination Survey, 1988–1994 Diabetes Care 1998 21: 518–524.

    Article  CAS  Google Scholar 

  24. Burt VL, Whelton P, Roccella EJ, Brown C, Cutler JA, Higgins M, Horan MJ, Labarthe D . Prevalence of hypertension in the US adult population. Results from the Third National Health and Nutrition Examination Survey, 1988–1991 Hypertension 1995 25: 305–313.

    Article  CAS  Google Scholar 

  25. World Health Organization . The Asia-Pacific perspective: redefining obesity World Health Organization: Geneva 2000

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to A Berber.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Berber, A., Gómez-Santos, R., Fanghänel, G. et al. Anthropometric indexes in the prediction of type 2 diabetes mellitus, hypertension and dyslipidaemia in a Mexican population. Int J Obes 25, 1794–1799 (2001). https://doi.org/10.1038/sj.ijo.0801827

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/sj.ijo.0801827

Keywords

This article is cited by

Search

Quick links