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Toxicology rethinks its central belief

Hormesis demands a reappraisal of the way risks are assessed.

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Figure 1: Hypothetical curves depicting (a) threshold, (b) linear non-threshold, and (c) hormetic dose-response models using cancer (number of tumours per animal) as the endpoint.

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Acknowledgements

Our work is sponsored by the Air Force Office of Scientific Research. Our views do not necessarily represent those of the Air Force Office of Scientific Research or the US Government.

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Calabrese, E., Baldwin, L. Toxicology rethinks its central belief. Nature 421, 691–692 (2003). https://doi.org/10.1038/421691a

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