Hostname: page-component-8448b6f56d-c4f8m Total loading time: 0 Render date: 2024-04-16T15:58:57.977Z Has data issue: false hasContentIssue false
  • English
  • Français

The developing world of DOHaD

Part of: Liggins Institute, New Zealand and the Japanese DOHaD Society

Published online by Cambridge University Press:  05 September 2017

K. Suzuki
K. Suzuki*
Affiliation:
Department of Pediatrics, Tokai University School of Medicine, Isehara, Japan
*
*Address for correspondence: K. Suzuki, Department of Pediatrics, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan. (Email dkswnd@tokai-u.jp)
Get access Rights & Permissions [Opens in a new window]

Abstract

Since its debut in a ground-breaking report by Barker and Osmond in 1986, the concept of the Developmental Origins of Health and Disease (DOHaD) has been further developed in several aspects. Its methodology and conclusions relating to proposed origins and outcomes of early life events have been developing and spreading internationally. Indeed, the DOHaD concept now seems to have influenced many fields of research. This article aims to briefly review why the DOHaD concept is important in biomedical science, how it has developed, is currently developing, and how it should develop in future.

Keywords

animaldevelopmental stageepidemiology/public healthhumanmolecular/cellularoutcome/systempolicy/economics
Type
Review
Information
Journal of Developmental Origins of Health and Disease , Volume 9 , Issue 3: Themed Issue: NZ-Japan , June 2018 , pp. 266 - 269
Check for updates
Copyright
© Cambridge University Press and the International Society for Developmental Origins of Health and Disease 2017 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Barker, DJ, Osmond, C. Infant mortality, childhood nutrition, and ischaemic heart disease in England and Wales. Lancet. 1986; 1, 1077–1081.CrossRefGoogle ScholarPubMed
2. Barker, DJ, Osmond, C. Diet and coronary heart disease in England and Wales during and after the Second World War. J Epidemiol Community Health. 1986; 40, 37–44.CrossRefGoogle ScholarPubMed
3. Barker, DJ, Winter, PD, Osmond, C, Margetts, B, Simmonds, SJ. Weight in infancy and death from ischaemic heart disease. Lancet. 1989; 2, 577–580.CrossRefGoogle ScholarPubMed
4. Barker, DJ, Gluckman, PD, Godfrey, KM, et al. Fetal nutrition and cardiovascular disease in adult life. Lancet. 1993; 341, 938–941.Google Scholar
5. Osmond, C, Barker, DJ, Winter, PD, Fall, CH, Simmonds, SJ. Early growth and death from cardiovascular disease in women. Br Med J. 1993; 307, 1519–1524.Google Scholar
6. Barker, DJ. The origins of the developmental origins theory. J Intern Med. 2007; 261, 412–417.Google Scholar
7. Holliday, R. Epigenetics: an overview. Dev Epigenet. 1994; 15, 453–457.Google ScholarPubMed
8. Reik, W, Dean, W, Walter, J. Epigenetic reprogramming in mammalian development. Science. 2001; 293, 1089–1093.Google Scholar
9. Gillman, MW, Barker, DJ, Bier, D, et al. Meeting report on the 3rd International Congress on Developmental Origins of Health and Disease (DOHaD). Pediatr Res. 2007; 61(Pt 1), 625–629.CrossRefGoogle ScholarPubMed
10. Gluckman, PD, Hanson, MA, Cooper, C, Thornburg, KL. Effect of in utero and early-life conditions on adult health and disease. N Engl J Med. 2008; 359, 61–73.Google Scholar
11. Haugen, AC, Schug, TT, Collman, G, Heindel, JJ. Evolution of DOHaD: the impact of environmental health sciences. J Dev Orig Health Dis. 2015; 6, 55–64.CrossRefGoogle ScholarPubMed
12. Rosenfeld, CS. ed. The Epigenome and Developmental Origins of Health and Disease. 2015. Academic Press Ltd: Cambridge, MA.Google Scholar
13. West, CE, Jenmalm, MC, Prescott, SL. The gut microbiota and its role in the development of allergic disease: a wider perspective. Clin Exp Allergy. 2015; 45, 43–53.Google Scholar
14. Drake, AJ, Tang, JI, Nyirenda, MJ. Mechanisms underlying the role of glucocorticoids in the early life programming of adult disease. Clin Sci (Lond). 2007; 113, 219–232.Google Scholar
15. Inskip, HM, Godfrey, KM, Robinson, SM, et al. Cohort profile: the Southampton Women’s Survey. Int J Epidemiol. 2006; 35, 42–48.Google Scholar
16. Olsen, J. The Danish National Birth Cohort – a data source for studying preterm birth. Acta Obstet Gynecol Sccand. 2005; 84, 539–540.CrossRefGoogle ScholarPubMed
17. Gillman, MW, Rich-Edwards, JW, Rifas-Shiman, SL, et al. Maternal age and other predictors of newborn blood pressure. J Pediatr. 2004; 144, 240–245.Google Scholar
18. Makrides, M, Gibson, RA, McPhee, AJ, et al. Effect of DHA supplementation during pregnancy on maternal depression and neurodevelopment of young children. J Am Med Assoc. 2010; 304, 1675–1683.Google Scholar
19. Uauy, R, Kain, J, Corvalan, C. How can the Developmental Origins of Health and Disease (DOHaD) hypothesis contribute to improving health in developing countries? Am J Clin Nutr. 2011; 94(Suppl.), 1759S–1764S.Google Scholar
20. Noncommunicable Diseases and Mental Health. Retrieved 25 August 2017 from http://www.who.int/nmh/en/.Google Scholar
21. 1,000 Days. Retrieved 25 August 2017 from https://thousanddays.org.Google Scholar
22. Jaddoe, VW, Mackenbach, JP, Moll, HA, et al. The Generation R Study: design and cohort profile. Eur J Epidemiol. 2006; 21, 475–484.Google Scholar
23. Landrigan, PJ, Transande, L, Thorpe, LE, et al. The National Children’s Study: a 21-year prospective study of 100,000 American children. Pediatrics. 2006; 118, 2173–2186.CrossRefGoogle Scholar
24. Tavener, M, Mooney, R, Thomson, C, Loxton, D. The Australian Longitudinal Study on Women’s Health: using focus groups to inform recruitment. JMIR Res Protoc. 2016; 5, e31.Google Scholar
25. Godfrey, KM, Cutfield, W, Chan, S-Y, et al. Nutritional intervention preconception and during pregnancy to maintain healthy glucose metabolism and offspring health (“NiPPeR”): study protocol for a randomized controlled trial. Trials. 2017; 18, 131–142.CrossRefGoogle Scholar
26. Kishi, R, Sasaki, S, Yoshioka, M, et al. Cohort profile: The Hokkaido Study on Environment and Children’s Health in Japan. Int J Epidemiol. 2011; 40, 611–618.Google Scholar
27. Kuriyama, S, Yaegashi, N, Nagami, F, et al. The Tohoku Medical Megabank project: design and mission. J Epidemiol. 2016; 26, 493–511.CrossRefGoogle ScholarPubMed
28. Gluckman, PD, Hanson, MA. Developmental and epigenetic pathways to obesity: an evolutionary-developmental perspective. Int J Obes (Lond). 2008; 32, S62–S71.Google Scholar
29. Calabrese, EJ, Baldwin, LA. U-shaped dose-responses in biology, toxicology, and public health. Annu Rev Public Health. 2001; 22, 15–33.Google Scholar
30. Crick, F. Central dogma of molecular biology. Nature. 1970; 227, 561–563.Google Scholar