Original articleHealth Outcomes Related to Early Adolescent Depression
Section snippets
Participants
The sample for the present analyses consisted of 705 adolescents (342 males and 363 females) involved in a study of maternal and offspring depression. The participants were selected from a study of children born between 1981 and 1984 at Mater Misericordiae Mothers Hospital in Brisbane, Queensland, the Mater-University Study of Pregnancy (MUSP) [20]. When the children were 15, the present investigators selected 900 families with diverse experiences in severity and chronicity of maternal
Data Analysis
Hierarchical ordinary least-squares and logistic regression analyses were used to investigate hypotheses regarding continuously distributed and dichotomous outcomes, respectively. Given that childhood health problems have been shown to predict the development of depression during late adolescence and early adulthood [27], all analyses controlled for chronic illness at age 5 years, as reported contemporaneously by the mother. The effects of socioeconomic status were controlled by including
Discussion
Building on prior research, this paper addressed the question of whether adolescents with a history of depressive disorders remain at risk for negative health outcomes in young adulthood even when current depression is taken into account. The analyses suggested that both objectively rated and self-rated general health during the transition to adulthood may be compromised among individuals who have experienced depressive disorders, and that these detriments to health are associated with higher
Acknowledgment
This research was supported in part by the National Institute of Mental Health Ruth L. Kirschenstein National Research Service Award T32- MH14584 (to D.K.-M.). This research was supported by NIMH R01MH5223901 (to C.H. and P.B.). We are grateful to the project staff in Brisbane, coordinated by Robyne Le Brocque, Ph.D., and Sascha Hardwicke, and to MUSP collaborators Jake Najman, William Bor, M.D., Michael O’Callaghan, M.D., and Gail Williams, Ph.D., of the University of Queensland.
References (36)
Clinical and health services relationships between major depression, depressive symptoms, and general medical illness
Biol Psychiatry
(2003)- et al.
Cross-sectional and prospective relationships between physical morbidity and depression in older adolescents
J Am Acad Child Adolesc Psychiatry
(1996) - et al.
Adult physical health outcomes of adolescent girls with conduct disorder, depression, and anxiety
J Am Acad Child Adolesc Psychiatry
(1998) Social and economic background and class inequalities in health among young adults
Soc Sci Med
(1991)- et al.
The global burden of disease: A comprehensive assessment of mortality and disability from diseases, injuries, and risk factors in 1990 and projected to 2020
(1996) - et al.
Cost-utility studies of depression management: A systematic review
Am J Psychiatry
(2004) - et al.
Cost-effectiveness of enhancing primary care depression management on an ongoing basis
Ann Fam Med
(2005) - et al.
The vital link between chronic disease and depressive disorders
Prev Chronic Dis
(2005) - et al.
Psychosocial factors and cardiovascular diseases
Annu Rev Public Health
(2005) - et al.
Asthma symptoms associated with depression and lower quality of life: A population survey
Med J Aust
(2003)
Depression as a risk factor for cardiovascular disease
Prim Psychiatry
Depression after myocardial infarction
Cardiol Rev
Psychiatric illness and cardiovascular disease risk
Epidemiol Rev
Depression and cardiac disease
Depress Anx
Correlates of depression in a representative nationwide sample of adolescents and young adults
Eur J Public Health
The role of self-assessed health in the relationship between gender and depressive symptoms among adolescents
J Pediatr Psychol
Epidemiology of DSM-III-R major depression and minor depression among adolescents and young adults in the National Comorbidity Survey
Depression and Anxiety
Prevalence and impact of chronic illness among adolescents
Am J Dis Child
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