Elsevier

Journal of Affective Disorders

Volume 287, 15 May 2021, Pages 352-353
Journal of Affective Disorders

Correspondence
No psychological vaccination: Vaccine hesitancy is associated with negative psychiatric outcomes among Israelis who received COVID-19 vaccination

https://doi.org/10.1016/j.jad.2021.03.064Get rights and content

Highlights

  • Israel is among the first populations to vaccinate large populations

  • Psychiatric morbidity has not been examined among vaccinated populations

  • Vaccine hesitancy was a major risk factor for such morbidity in this population

Abstract

Background

The widespread COVID-19 vaccination program, issued by the Israel Government, provides a unique opportunity to examine psychiatric morbidity and vaccine attitudes among individuals who have already been vaccinated. Accordingly, the current study examined how vaccine hesitancy contributes to clinical levels of depression, anxiety, and peritraumatic stress among individuals who had received COVID-19 vaccinations.

Methods

We analyzed data obtained from 254 vaccinated individuals, and assessed vaccine hesitancy, depression, anxiety, and peritraumatic distress, as well as several demographic, health, and COVID-19-related factors.

Results

Logistic regressions demonstrated that above and beyond socio-demographic, health, and COVID-19-related factors, COVID-19 vaccine hesitancy was the most prominent risk factor for anxiety, depression, and peritraumatic distress. Higher levels of vaccine hesitancy were found to double the risk for depression and peritraumatic stress (ORs > 2), and to triple the risk for anxiety (OR > 3).

Limitations

A cross-sectional design; a preliminary study requiring further investigation

Conclusions

This study points to the importance of vaccine hesitancy among vaccinated populations and provides knowledge regarding its associations with negative psychiatric outcomes. These findings may offer important information for healthcare practitioners and policy makers in their attempt to encourage individuals to receive COVID-19 vaccinations and emphasize the need to further understand the underlying mechanisms of psychiatric morbidity among vaccinated individuals.

Keywords

COVID-19
Psychiatric morbidity
Vaccinated populations
Vaccination hesitancy

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