20.° Simposio científico obesidad hoy
Obesity—a modern pandemic: the burden of disease

https://doi.org/10.1016/S1575-0922(13)70015-9Get rights and content

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  • Cascade regulation of PPARγ<sup>2</sup> and C/EBPα signaling pathways by celastrol impairs adipocyte differentiation and stimulates lipolysis in 3T3-L1 adipocytes

    2016, Metabolism: Clinical and Experimental
    Citation Excerpt :

    Obesity is relevant to a number of pathological disorders, such as type 2 diabetes, hypertension, hyperlipidemia, cardiovascular disease, respiratory complications, osteoarthritis, and cancer [1]. Given the global epidemic and its association with many life-threatening chronic diseases, obesity induces a main health problem [2–3]. Adipose tissue mass is determined by processes regulating adipocyte number and size [4–5].

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