Is breast cancer caused by late exposure to a common virus?
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Possible role of EBV in breast cancer and other unusually EBV-associated cancers
2011, Cancer LettersCitation Excerpt :The etiology of breast cancer is poorly understood; however, genetic background and hormonal effects are believed to play important roles in its development. Late exposure to a common virus, such as human cytomegalovirus, has been also suggested as a risk factor for breast carcinomas [37]. Epidemiological data on breast cancer exhibit similarities to those of Hodgkin’s disease in young adulthood and suggest that delayed infection with EBV may be a risk for breast cancer [38].
Viral hit and run-oncogenesis: Genetic and epigenetic scenarios
2011, Cancer LettersCitation Excerpt :Throughout female populations worldwide, breast cancer risk is inversely associated with the risk of contracting so called “microbial cancers” (i.e. hepatitis B virus-hepatic cancer, H. pylori-gastric cancer, human papillomavirus-cervical cancer) in a strikingly hyperbolic way [128]. The delayed exposure to a common infectious agent has been linked with breast cancer [129,130], and cells resembling HRS cells have been found in breast tumors, too [131]. Consequently, delayed primary EBV-infection was shown to not only correlate with subsequent HL, but also with breast cancer susceptibility [132].
The genetic algorithm for breast tumor diagnosis-The case of DNA viruses
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