Elsevier

Chemosphere

Volume 29, Issues 9–11, November–December 1994, Pages 2405-2411
Chemosphere

Toxicology
Cognitive development in Yucheng children

https://doi.org/10.1016/0045-6535(94)90409-XGet rights and content

Abstract

We have been following up the biological and mental development of children exposed prenatally to polychlorinated biphenyls and their contaminants(Yucheng children). When we started this 12-year follow-up study in August 1985, 118 Yucheng children we assigned a non-exposed child matched by sex, age, locality of residence, mother's age, socio-economic status of the family. This article reports the cognitive aspect of the development of Yucheng children as compared to their matched controls. A consistent tendency which indicates that Yucheng children score lower in each kind of measurement tool at each age level has been observed. This seems to imply that congenitally exposure to PCBs and their contaminants has long-term adverse effects on the cognitive development of human being.

References (12)

There are more references available in the full text version of this article.

Cited by (44)

  • Gestational dioxin exposure suppresses prolactin-stimulated nursing in lactating dam rats to impair development of postnatal offspring

    2020, Biochemical Pharmacology
    Citation Excerpt :

    For example, treating pregnant rats with TCDD produces postnatal offspring with reduced body weight and length [5] and impaired learning memory [6]. A growing number of epidemiological studies have proposed negative correlations between dioxin body burden in mothers and their offspring development, such as body weight [7], learning, and physical ability [8,9]. Several of these appear highly serious, because they are caused by low-dose exposure and have long-lasting effects persisting into adulthood, after the chemicals have already been cleared from the body.

  • YY162 prevents ADHD-like behavioral side effects and cytotoxicity induced by Aroclor1254 via interactive signaling between antioxidant potential, BDNF/TrkB, DAT and NET

    2014, Food and Chemical Toxicology
    Citation Excerpt :

    PCB-exposed animals are toxico-behaviorally well-characterized environmental models of ADHD (Berger et al., 2001; Das Banerjee et al., 2008; Rice, 1998, 1999). There is a great deal of evidence that children born to females who consumed PCB-contaminated food during pregnancy show delayed developmental milestones, cognitive deficits, and behavioral problems (Jacobson and Jacobson, 1996; Lai et al., 1994; Yu et al., 1994). Under our experimental conditions, Aroclor1254-exposed mice exhibited the three core symptoms of ADHD; i.e., hyperactivity, impulsivity, and impaired attention.

  • Occupational neurotoxic diseases in Taiwan

    2012, Safety and Health at Work
    Citation Excerpt :

    Approximately half the victims experienced CNS disorder, including memory impairment, mental dullness, cognitive dysfunction, and learning difficulties [12,13]. Dose-dependent cognitive impairments in learning ability, attention, and visual memory were particularly noted in children born to women who had previously been exposed to PCB [13,14]. Furthermore, PNS symptoms such as weakness, paresthesia and pain in the distal extremities with a sensory predominant polyneuropathy were commonly noted [15,16].

  • Exposure to Environmental Chemicals and Developmental Risk: Contributions from Studies with Monkeys

    2008, Primate Models of Children's Health and Developmental Disabilities
View all citing articles on Scopus
View full text