Abstract
From 1962 to 1982 1,623 consecutive patients were curatively operated for colorectal adenocarcinoma. For all patients cancer specific mortality rates were registered and the influence of the following prognostic factors was evaluated: tumour stage and grade, adenomas, age, sex and tumour site. In a multivariate Cox analysis, with backward elimination of non-significant factors at a 10% level, Dukes' C stage, poor differentiation, and age between 40 and 60 years at onset of carcinoma reached independent prognostic significance.
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References
Howard EW, Cavallo C, Hovey JM, Nelson TG (1975) Colon and rectal cancer in the young adult. Ann Surg 41:260–265
Simstein NL, Kovalcik PJ, Cross GH (1978) Colorectal cancer in patients less than 40 years of age. Dis Colon Rectum 21:169–171
Hall A, Coffey RJ (1961) Cancer of the large bowel in the young patient. Am J Surg 102:66–72
Adkins RB, DeLozier JB, McKnight WG, Waterhouse G (1987) Carcinoma of the colon in patients 35 years of age and younger. Ann Surg 53:141–145
D'Onofrio GMD, Tan EGC (1985) Is colorectal carcinoma in the young a more deadly disease? Aust NZ J Surg 55:537–540
Behbehani A, Sakwa M, Erlichman R, Maguire P, Friedman S, Steele GD, Wilson RE (1985) Colorectal carcinoma in patients under age 40. Ann Surg 202:610–614
Enker WA, Paloyan E, Kirsner JB (1977) Carcinoma of the colon in the adolescent. Am J Surg 133:737–741
Mayo CW, Pagtalunana RJG (1963) Malignancy of colon and rectum in patients under 30 years of age. Surgery 53:711–718
Bülow S (1980) Colorectal cancer in patients less than 40 years of age in Denmark 1943–1967. Dis Colon Rectum 23:327–336
Järvinen HJ, Turunen MJ (1984) Colorectal carcinoma before 40 years of age: prognosis and predisposing factors. Scand J Gastroenterol 19:634–638
Beckman EN, Gathright JB, Ray JE (1984) A potentially brighter prognosis for colon carcinoma in the third and fourth decades. Cancer 54:1478–1481
Umbleby HC, Williamson RCN (1984) Carcinoma of the large bowel in the first four decades. Br J Surg 71:272–277
Taylor MC, Pounder D, Ali-Rhida NH, Bodurtha A, Mac-Mullin EC (1988) Prognostic factors in colorectal carcinoma of young adults. Can J Surg 31:150–153
Kronborg O, Hage E, Fenger C, Deichgraeber E (1986) Do synchronous adenomas influence prognosis after radical surgery for colorectal cancer. Int J Colored Dis 1:99–103
Brown BW, Hollander M (1977) Statistics: a biomedical introduction. Wiley, New York, pp 211–215
Peto R, Pike MC, Armitage P, Breslow NE, Cox DR, Howard V, Mantel N, McPherson K, Peto J, Smith PG (1976) Design and analysis of randomized clinical trials requiring prolonged observation of each patient. Br J Cancer 34:585–612
Umpleby HC, Bristol JB, Williamson RCN (1984) Survival of 727 patients with single carcinomas of the large bowel. Dis Colon Rectum 27:803–810
Taat CW, Bernsen RMD, Nakelkerke NJD, Beutel de la Riviera A (1981) A multivariate analysis of the prognosis of carcinoma of the colon. Neth J Surg 33:57–62
Turunen MJ, Peltokallio P (1983) Surgical results in 657 patients with colorectal cancer. Dis Colon Rectum 26:606–612
Gardner B, Dotan J, Shaikh L, Feldman J, Herbsman H, Alfonso A, Iyer SK (1981) The influence of age upon the survival of adult patients with carcinoma of the colon. Surg Gynecol Obstet 153:366–368
McDermot FT, Hughes ESR, Pihl E, Milne BJ, Price AB (1981) Comparative results of surgical management of single carcinomas of the colon and rectum: a series of 1939 patients managed by one surgeon. Br J Surg 68:850–855
Habib NA, Peck MA, Sawyer CN, Blaxland JW, Luck RJ (1983) An analysis of the outcome of 301 malignant colorectal tumors. Dis Colon Rectum 26:601–605
Malcolm AW, Perencevich NP, Olson RM, Hanley JA, Chaffey JT, Wilson RE (1981) Analysis of recurrence patterns following curative resection for carcinoma of the colon and rectum. Surg Gynecol Obstet 152:131–136
Griffin MR; Bergstral EJ, Coofey RJ, Beart RW Jr, Melton LJ (1987) Predictor of survival after curative resection of carcinoma of the colon and rectum. Cancer 60:2318–2324
Fielding LP, Phillips RKS, Fry JS, Hittinger R (1986) Prediction of outcome after curative resection for large bowel cancer. Lancet 2:904–907
Halvorsen TB, Seim E (1987) Tumour site: a prognostic factor in colorectal cancer? A multivariate analysis. Scand J Gastroenterol 22:124–128
Chapuis PH, Dent OF, Fisher R, Newland RC, Pheils MT, Smyth E, Colquhoun K (1985) A multivariate analysis of clinical and pathological variables in the prognosis after resection of large bowel cancer. Br J Surg 72:698–702
Hoff G, Vatn M, Gjone E, Larsen S, Sauar J (1985) Epidemiology of polyps in the rectum and sigmoid colon. Design of a population study. Scand J Gastroenterol 20:351–355
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Svendsen, L.B., Sørensen, C., Kjersgaard, P. et al. The influence of age upon the survival after curative operation for colorectal cancer. Int J Colorect Dis 4, 123–127 (1989). https://doi.org/10.1007/BF01646871
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DOI: https://doi.org/10.1007/BF01646871