Characteristics of baseline QRISK factors by 10-year incident CVD
| Incident CVD | All | ||
| No | Yes | ||
| Number of participants | 69 683 | 5097 | 74 780 |
| Age, sex and socioeconomic factors | |||
| Men, % | 42.0 | 59.8 | 43.3 |
| Baseline age, years | 55.0 (8.0) | 59.6 (7.0) | 55.3 (8.0) |
| White, % | 94.8 | 95.7 | 94.9 |
| Townsend Deprivation Index* | 1.5 (2.9) | 1.3 (3.0) | 1.4 (3.0) |
| Anthropometry, blood pressure and lipids by clinical chemistry | |||
| Body mass index, kg/m2 | 26.9 (4.5) | 27.9 (4.6) | 27.0 (4.6) |
| Systolic blood pressure, mm Hg | 136.2 (17.9) | 143.7 (18.1) | 136.7 (18.4) |
| SD between two readings,† mm Hg | 5.1 (4.0) | 5.5 (4.2) | 5.2 (4.0) |
| Total cholesterol to HDL-C ratio | 4.2 (1.1) | 4.5 (1.2) | 4.2 (1.1) |
| Smoking intensity, % | |||
| Ex-smoker | 32.4 | 35.7 | 32.7 |
| Light smoker (<10 per day) | 4.8 | 4.9 | 4.8 |
| Moderate smoker (10–19 per day) | 2.9 | 4.7 | 3.0 |
| Heavy smoker (≥20 per day) | 2.3 | 4.6 | 2.4 |
| Family history of heart disease,‡ % | 39.5 | 50.5 | 40.2 |
| Disease and medication history, % | |||
| Type 1 diabetes | 0.3 | 0.6 | 0.3 |
| Type 2 diabetes | 1.6 | 3.6 | 1.7 |
| Chronic kidney disease (stage 3,4,5) | 1.5 | 2.8 | 1.6 |
| Atrial fibrillation | 0.8 | 2.6 | 0.9 |
| Migraines | 4.5 | 5.2 | 4.6 |
| Rheumatoid arthritis | 1.1 | 2.4 | 1.2 |
| Systemic lupus erythematosus | 0.1 | 0.3 | 0.1 |
| Severe mental illness§ | 5.0 | 5.5 | 5.0 |
| Erectile dysfunction | 0.2 | 0.5 | 0.2 |
| Hypertension treatment | 11.6 | 23.0 | 12.3 |
| Atypical antipsychotic medication | 0.2 | 0.2 | 0.2 |
| Regular steroid tablets | 0.7 | 1.8 | 0.8 |
Sex-adjusted characteristics of QRISK factors at baseline by 10-year incident CVD. Incident CVD defined as the first-ever coronary heart disease, ischaemic stroke or transient ischaemic attack. Continuous variables are presented as mean (SD) and categorical variables are presented as column percentages.
*Higher values indicate higher levels of material deprivation.
†QRISK asks for standard deviation of systolic blood pressure values recorded in the 5 years before study entry, but UK Biobank only provided two automated or manual readings at study entry.
‡QRISK asks for the family history in first-degree relatives aged less than 60 years, but UK Biobank only identified family history in first degree relatives in all ages.
§Includes schizophrenia, bipolar disorder and moderate/severe depression.
CVD, cardiovascular disease; HDL-C, high-density lipoproteins cholesterol.