Table 1

Characteristics of baseline QRISK factors by 10-year incident CVD

Incident CVDAll
Number of participants69 683509774 780
Age, sex and socioeconomic factors
 Men, %42.059.843.3
 Baseline age, years55.0 (8.0)59.6 (7.0)55.3 (8.0)
 White, %94.895.794.9
 Townsend Deprivation Index*1.5 (2.9)1.3 (3.0)1.4 (3.0)
Anthropometry, blood pressure and lipids by clinical chemistry
 Body mass index, kg/m2 26.9 (4.5)27.9 (4.6)27.0 (4.6)
 Systolic blood pressure, mm Hg136.2 (17.9)143.7 (18.1)136.7 (18.4)
  SD between two readings,† mm Hg5.1 (4.0)5.5 (4.2)5.2 (4.0)
 Total cholesterol to HDL-C ratio4.2 (1.1)4.5 (1.2)4.2 (1.1)
Smoking intensity, %
 Light smoker (<10 per day)
 Moderate smoker (10–19 per day)
 Heavy smoker (≥20 per day)
Family history of heart disease,‡ %39.550.540.2
Disease and medication history, %
 Type 1 diabetes0.30.60.3
 Type 2 diabetes1.63.61.7
 Chronic kidney disease (stage 3,4,5)
 Atrial fibrillation0.82.60.9
 Rheumatoid arthritis1.12.41.2
 Systemic lupus erythematosus0.10.30.1
 Severe mental illness§
 Erectile dysfunction0.20.50.2
 Hypertension treatment11.623.012.3
 Atypical antipsychotic medication0.20.20.2
 Regular steroid tablets0.71.80.8
  • Sex-adjusted characteristics of QRISK factors at baseline by 10-year incident CVD. Incident CVD defined as the first-ever coronary heart disease, ischaemic stroke or transient ischaemic attack. Continuous variables are presented as mean (SD) and categorical variables are presented as column percentages.

  • *Higher values indicate higher levels of material deprivation.

  • †QRISK asks for standard deviation of systolic blood pressure values recorded in the 5 years before study entry, but UK Biobank only provided two automated or manual readings at study entry.

  • ‡QRISK asks for the family history in first-degree relatives aged less than 60 years, but UK Biobank only identified family history in first degree relatives in all ages.

  • §Includes schizophrenia, bipolar disorder and moderate/severe depression.

  • CVD, cardiovascular disease; HDL-C, high-density lipoproteins cholesterol.