The influence of medication use for mental disorders and sociodemographics on exiting paid employment among secondary vocational education graduates (N=866 545) and higher education graduates (N=969 885) who entered paid employment during the follow-up period
Exit from paid employment | ||||
Secondary vocational education (N=8 66 545) | Higher education (N=9 69 885) | |||
Unadjusted | Adjusted* | Unadjusted | Adjusted* | |
HR (95% CI) | HR (95% CI) | HR (95% CI) | HR (95% CI) | |
Age at graduation | 0.94 (0.94 to 0.94) | 0.93 (0.93 to 0.93) | 0.93 (0.93 to 0.93) | 0.92 (0.92 to 0.93) |
Sex | ||||
Female | 1.29 (1.28 to 1.30) | 1.27 (1.26 to 1.28) | 1.17 (1.16 to 1.18) | 1.12 (1.11 to 1.13) |
Male | Ref. | Ref. | Ref. | Ref. |
Transgender | 2.03 (1.77 to 2.33) | 1.95 (1.70 to 2.24) | 2.02 (1.70 to 2.41) | 1.89 (1.59 to 2.25) |
Migration background | ||||
Native Dutch | Ref. | Ref. | Ref. | Ref. |
Moroccan | 2.39 (2.35 to 2.43) | 2.42 (2.38 to 2.46) | 1.57 (1.53 to 1.61) | 1.63 (1.59 to 1.67) |
Turkish | 2.20 (2.17 to 2.24) | 2.22 (2.19 to 2.26) | 1.59 (1.55 to 1.63) | 1.66 (1.62 to 1.70) |
Antillean | 2.15 (2.12 to 2.18) | 2.33 (2.30 to 2.37) | 1.52 (1.49 to 1.55) | 1.63 (1.60 to 1.66) |
Other European | 1.43 (1.40 to 1.46) | 1.50 (1.46 to 1.53) | 1.37 (1.34 to 1.40) | 1.45 (1.41 to 1.48) |
Other non-European | 1.95 (1.93 to 1.97) | 2.13 (2.11 to 2.16) | 1.47 (1.46 to 1.49) | 1.58 (1.57 to 1.60) |
Medication use† | ||||
Any | 1.28 (1.26 to 1.30) | 1.42 (1.40 to 1.44) | 1.30 (1.27 to 1.32) | 1.41 (1.38 to 1.44) |
Antipsychotics | 1.69 (1.62 to 1.76) | 1.91 (1.83 to 1.99) | 1.66 (1.56 to 1.77) | 1.82 (1.71 to 1.94) |
Anxiolytics | 1.38 (1.32 to 1.46) | 1.42 (1.35 to 1.49) | 1.35 (1.28 to 1.43) | 1.39 (1.31 to 1.47) |
Hypnotics and sedatives | 1.50 (1.39 to 1.63) | 1.57 (1.45 to 1.71) | 1.38 (1.26 to 1.51) | 1.51 (1.38 to 1.66) |
Antidepressants | 1.25 (1.21 to 1.28) | 1.44 (1.40 to 1.47) | 1.29 (1.26 to 1.33) | 1.41 (1.38 to 1.45) |
Psychostimulants | 1.23 (1.20 to 1.26) | 1.36 (1.33 to 1.39) | 1.29 (1.25 to 1.33) | 1.40 (1.36 to 1.45) |
Drugs for addiction | 1.23 (1.09 to 1.40) | 1.58 (1.39 to 1.80) | 1.32 (1.09 to 1.60) | 1.50 (1.24 to 1.82) |
*Adjusted for sociodemographics (age at graduation, sex, migration background).
†Individuals not using medication were used as a reference.