Table 3

The influence of medication use for mental disorders and sociodemographics on exiting paid employment among secondary vocational education graduates (N=866 545) and higher education graduates (N=969 885) who entered paid employment during the follow-up period

Exit from paid employment
Secondary vocational education (N=8 66 545)Higher education (N=9 69 885)
UnadjustedAdjusted*UnadjustedAdjusted*
HR (95% CI)HR (95% CI)HR (95% CI)HR (95% CI)
Age at graduation0.94 (0.94 to 0.94)0.93 (0.93 to 0.93)0.93 (0.93 to 0.93)0.92 (0.92 to 0.93)
Sex
 Female1.29 (1.28 to 1.30)1.27 (1.26 to 1.28)1.17 (1.16 to 1.18)1.12 (1.11 to 1.13)
 MaleRef.Ref.Ref.Ref.
 Transgender2.03 (1.77 to 2.33)1.95 (1.70 to 2.24)2.02 (1.70 to 2.41)1.89 (1.59 to 2.25)
Migration background
 Native DutchRef.Ref.Ref.Ref.
 Moroccan2.39 (2.35 to 2.43)2.42 (2.38 to 2.46)1.57 (1.53 to 1.61)1.63 (1.59 to 1.67)
 Turkish2.20 (2.17 to 2.24)2.22 (2.19 to 2.26)1.59 (1.55 to 1.63)1.66 (1.62 to 1.70)
 Antillean2.15 (2.12 to 2.18)2.33 (2.30 to 2.37)1.52 (1.49 to 1.55)1.63 (1.60 to 1.66)
 Other European1.43 (1.40 to 1.46)1.50 (1.46 to 1.53)1.37 (1.34 to 1.40)1.45 (1.41 to 1.48)
 Other non-European1.95 (1.93 to 1.97)2.13 (2.11 to 2.16)1.47 (1.46 to 1.49)1.58 (1.57 to 1.60)
Medication use†
 Any1.28 (1.26 to 1.30)1.42 (1.40 to 1.44)1.30 (1.27 to 1.32)1.41 (1.38 to 1.44)
 Antipsychotics1.69 (1.62 to 1.76)1.91 (1.83 to 1.99)1.66 (1.56 to 1.77)1.82 (1.71 to 1.94)
 Anxiolytics1.38 (1.32 to 1.46)1.42 (1.35 to 1.49)1.35 (1.28 to 1.43)1.39 (1.31 to 1.47)
 Hypnotics and sedatives1.50 (1.39 to 1.63)1.57 (1.45 to 1.71)1.38 (1.26 to 1.51)1.51 (1.38 to 1.66)
 Antidepressants1.25 (1.21 to 1.28)1.44 (1.40 to 1.47)1.29 (1.26 to 1.33)1.41 (1.38 to 1.45)
 Psychostimulants1.23 (1.20 to 1.26)1.36 (1.33 to 1.39)1.29 (1.25 to 1.33)1.40 (1.36 to 1.45)
 Drugs for addiction1.23 (1.09 to 1.40)1.58 (1.39 to 1.80)1.32 (1.09 to 1.60)1.50 (1.24 to 1.82)
  • *Adjusted for sociodemographics (age at graduation, sex, migration background).

  • †Individuals not using medication were used as a reference.