Table 2

Description of the comorbidity patterns according to selected variables, Italy and Switzerland, 1991–2008

Healthy (%)Metabolic disorders (%)Hysterectomy, uterine fibroids and bilateral ovariectomy (%)Breast diseases (%)Ovarian cysts and unilateral ovariectomy (%)
Cluster size57.6424.3812.882.692.40
Case control status
 Case48.0148.4939.3859.3643.68
 Control51.9951.5160.6240.6456.32
Centre
 Italy82.0281.4872.1371.9678.15
 Switzerland17.9818.5227.8728.0421.85
Age (years)
 <4526.2211.794.6114.9618.03
 45–5429.6621.6726.2438.7529.40
 55–6425.6533.5939.1727.2827.46
 65+18.4732.9529.9819.0125.11
Education (years)
 <741.5551.3347.9731.7939.16
 7–1133.1431.933.3837.3339.37
 12+25.3116.7618.6530.8821.46
Parity
 018.3215.2313.7718.9223.96
 121.6521.2918.7822.7821.72
 236.1634.3741.8339.6835.18
 3+23.8729.1125.6318.6119.15
Menopausal status (age at menopause)
 Pre47.9326.872.8641.7830.83
 Post (<50)18.8225.7672.2721.9737.59
 Post (50+)33.2547.3624.8736.2531.58
BMI
 <18.53.352.031.115.912.97
 18.5–24.957.5835.342.4258.1159.22
 25–29.931.2333.1938.7125.630.01
 30+7.8329.4817.7610.387.80
FH
 No93.5292.8392.3884.7292.67
 Yes6.487.177.6215.287.33
OC ever use
 Never83.6791.1193.0078.3784.76
 Ever16.338.897.0021.6315.24
 HRT ever use
 Never92.5691.2478.1488.0384.73
 Ever7.448.7621.8611.9715.27
Smoking habit (n cigarettes/day)
 Non-smokers65.2471.8366.1558.7357.55
 Ex smokers10.459.7712.2414.2114.21
 Current (<15)13.839.5210.5112.0214.12
 Current (³15)10.488.8811.115.0314.11
Alcohol drinking (weekly units)
 037.8440.4540.7832.7730.12
 <720.6919.6618.5121.6924.46
 7–1316.9616.6519.2123.8221.11
 14+24.5123.2321.521.7224.32
  • BMI, body mass index; FH, family history of breast cancer in first degree relatives; HRT, hormonal replacement therapy; OC, oral contraceptive.