Maximum personal annual income quintiles | 1 | 2 | 3 | 4 | 5 | P value |
n=21 057 | n=18 161 | n=18 077 | n=18 406 | n=18 816 | ||
Mean income, € | 0±0 | 2517±1119 | 7209±1743 | 15226±3090 | 43063±21 882 | <0.0001 |
Mean cohort entry year | 2012±3 | 2013±3 | 2013±3 | 2013±3 | 2014±3 | <0.0001 |
Demographics | ||||||
Mean age, years | 84.9±5.7 | 83.6±5.4 | 82.6±5.2 | 82.0±5.2 | 81.8±5.3 | <0.0001 |
Female gender | 4725 (22.4) | 5131 (29.3) | 6382 (35.3) | 8097 (44.0) | 10 689 (56.8) | <0.0001 |
Highest educational level | <0.0001 | |||||
Category 1 | 17 928 (85.1) | 14 758 (81.3) | 13 876 (76.8) | 11 655 (63.3) | 7032 (37.4) | |
Category 2 | 2770 (13.2) | 2958 (16.3) | 3390 (18.8) | 4134 (22.5) | 3251 (17.3) | |
Category 3 | 359 (1.7) | 445 (2.5) | 811 (4.5) | 2617 (14.2) | 8533 (45.3) | |
Comorbidities | ||||||
Abnormal liver function | 50 (0.2) | 45 (0.2) | 58 (0.3) | 60 (0.3) | 66 (0.4) | <0.0001 |
Abnormal renal function | 1033 (4.9) | 899 (5.0) | 969 (5.4) | 891 (4.8) | 947 (5.0) | <0.0001 |
Alcohol abuse | 235 (1.1) | 233 (1.3) | 291 (1.6) | 285 (1.5) | 308 (1.6) | <0.0001 |
Diabetes | 4882 (23.2) | 4300 (23.7) | 4407 (24.4) | 4284 (23.3) | 3807 (20.2) | <0.0001 |
Dyslipidaemia | 8944 (42.5) | 8877 (48.9) | 9569 (52.9) | 10 017 (54.4) | 10 218 (54.3) | <0.0001 |
Heart failure | 6850 (32.5) | 4985 (27.4) | 4375 (24.2) | 3931 (21.4) | 3382 (18.0) | <0.0001 |
Hypertension | 16 714 (79.4) | 14 792 (81.4) | 14 771 (81.7) | 14 953 (81.2) | 14 782 (78.6) | <0.0001 |
Prior bleeding | 2387 (11.3) | 2116 (11.7) | 2169 (12.0) | 2347 (12.8) | 2396 (12.7) | <0.0001 |
Prior myocardial infarction | 2628 (12.5) | 2038 (11.2) | 1958 (10.8) | 1981 (10.8) | 1815 (9.6) | <0.0001 |
Vascular disease | 7930 (37.7) | 6556 (36.1) | 6401 (35.4) | 6476 (35.2) | 6195 (32.9) | <0.0001 |
Dementia | 2321 (11.0) | 1744 (9.6) | 1475 (8.2) | 1357 (7.4) | 1223 (6.5) | <0.0001 |
Psychiatric disorder | 2253 (10.7) | 1923 (10.6) | 2087 (11.5) | 1964 (10.7) | 1822 (9.7) | <0.0001 |
CHA2DS2-VASc score | 4.5±1.1 | 4.4±1.1 | 4.3±1.1 | 4.1±1.1 | 3.9±1.1 | <0.0001 |
OAC before stroke occurrence | 12 698 (60.3) | 12 687 (69.9) | 13 587 (75.2) | 14 148 (76.9) | 14 614 (77.7) | <0.0001 |
Values denote n (%) or mean (SD).
Vascular disease: prior myocardial infarction and/or peripheral vascular disease.
CHA2DS2-VASc, congestive heart failure, hypertension, age ≥75 years, diabetes, history of stroke or TIA, vascular disease, age 65–74 years, sex category (female); OAC, oral anticoagulant.