Impact of maximum personal annual income on 10-year first-ever ischaemic stroke and all-cause mortality among patients with atrial fibrillation in different age strata
| Subgroups and outcomes | Events (%) | Patient years | Incidence/year (%) | Unadjusted risk estimates | Adjusted risk estimates |
| <65 years | |||||
| Stroke | |||||
| Maximum personal annual income | |||||
| ≤€12 000 | 592 (5.8) | 55 132 | 1.1 (1.0 to 1.2) | Reference | Reference |
| €13 000–€26 000 | 357 (3.2) | 62 459 | 0.6 (0.5 to 0.6) | 0.603, 0.529 to 0.688 | 0.693, 0.606 to 0.793 |
| €27 000–€36 000 | 300 (2.8) | 58 819 | 0.5 (0.5 to 0.6) | 0.571, 0.498 to 0.657 | 0.712, 0.615 to 0.824 |
| €37 000–€53 000 | 274 (2.5) | 59 609 | 0.5 (0.4 to 0.5) | 0.519, 0.449 to 0.599 | 0.668, 0.572 to 0.781 |
| ≥€54 000 | 242 (2.2) | 60 063 | 0.4 (0.4 to 0.5) | 0.456, 0.392 to 0.530 | 0.600, 0.504 to 0.713 |
| All-cause mortality | |||||
| Maximum personal annual income quintiles | |||||
| ≤€12 000 | 2663 (26.2) | 55 559 | 4.8 (4.6 to 5.0) | Reference | Reference |
| €13 000–€26 000 | 1241 (11.3) | 62 598 | 2.0 (1.9 to 2.1) | 0.415, 0.388 to 0.444 | 0.600, 0.560 to 0.644 |
| €27 000–€36 000 | 700 (6.4) | 58 873 | 1.2 (1.1 to 1.3) | 0.248, 0.228 to 0.269 | 0.428, 0.392 to 0.468 |
| €37 000–€53 000 | 581 (5.3) | 59 650 | 1.0 (0.9 to 1.1) | 0.203, 0.185 to 0.222 | 0.359, 0.326 to 0.396 |
| ≥€54 000 | 483 (4.5) | 60 130 | 0.8 (0.7 to 0.9) | 0.168, 0.152 to 0.185 | 0.299, 0.268 to 0.334 |
| 65–74 years | |||||
| Stroke | |||||
| Maximum personal annual income | |||||
| ≤€4000 | 832 (7.8) | 49 576 | 1.7 (1.6 to 1.8) | Reference | Reference |
| €5000–€12 000 | 713 (6.5) | 52 836 | 1.3 (1.3 to 1.5) | 0.881, 0.798 to 0.974 | 0.879, 0.795 to 0.973 |
| €13 000–€22 000 | 587 (5.4) | 50 673 | 1.2 (1.1 to 1.3) | 0.790, 0.710 to 0.878 | 0.780, 0.700 to 0.870 |
| €23 000–€39 000 | 546 (4.8) | 46 539 | 1.2 (1.1 to 1.3) | 0.845, 0.758 to 0.942 | 0.840, 0.747 to 0.945 |
| ≥€40 000 | 431 (3.9) | 44 915 | 1.0 (0.9 to 1.1) | 0.710, 0.631 to 0.798 | 0.716, 0.625 to 0.820 |
| All-cause mortality | |||||
| Maximum personal annual income quintiles | |||||
| ≤€4000 | 3619 (33.9) | 50 159 | 7.2 (7.0 to 7.5) | Reference | Reference |
| €5000–€12 000 | 2543 (23.2) | 53 352 | 4.8 (4.6 to 5.0) | 0.663, 0.630 to 0.697 | 0.681, 0.647 to 0.717 |
| €13 000–€22 000 | 1984 (18.1) | 51 091 | 3.9 (3.7 to 4.1) | 0.539, 0.511 to 0.570 | 0.567, 0.536 to 0.599 |
| €23 000–€39 000 | 1498 (13.2) | 46 822 | 3.2 (3.0 to 3.4) | 0.440, 0.414 to 0.468 | 0.488, 0.457 to 0.521 |
| ≥€40 000 | 1196 (10.8) | 45 123 | 2.7 (2.5 to 2.8) | 0.364, 0.341 to 0.389 | 0.411, 0.382 to 0.443 |
| ≥75 years | |||||
| Stroke | |||||
| Maximum personal annual income | |||||
| <€1000 | 2494 (11.8) | 62 759 | 4.0 (3.8 to 4.1) | Reference | Reference |
| €1000–€4000 | 1920 (10.6) | 60 526 | 3.2 (3.0 to 3.3) | 0.921, 0.867 to 0.977 | 0.981, 0.924 to 1.042 |
| €5000–€10 000 | 1696 (9.4) | 62 727 | 2.7 (2.6 to 2.8) | 0.850, 0.800 to 0.905 | 0.948, 0.890 to 1.009 |
| €11 000–€21 000 | 1665 (9.0) | 62 684 | 2.7 (2.5 to 2.8) | 0.857, 0.806.0.912 | 0.986, 0.923 to 1.052 |
| ≥€22 000 | 1614 (8.6) | 63 788 | 2.5 (2.4 to 2.7) | 0.838, 0.787 to 0.897 | 0.991, 0.922 to 1.065 |
| All-cause mortality | |||||
| Maximum personal annual income quintiles | |||||
| <€1000 | 14 078 (66.9) | 64 831 | 21.7 (21.4 to 22.1) | Reference | Reference |
| €1000–€4000 | 9919 (54.6) | 62 133 | 16.0 (15.7 to 16.8) | 0.741, 0.722 to 0.760 | 0.841, 0.820 to 0.863 |
| €5000–€10 000 | 7987 (44.2) | 64 006 | 12.5 (12.2 to 12.8) | 0.580, 0.564 to 0.596 | 0.730, 0.709 to 0.751 |
| €11 000–€21 000 | 7288 (40.0) | 64 041 | 11.3 (11.1 to 11.6) | 0.529, 0.515 to 0.545 | 0.690, 0.670 to 0.711 |
| ≥€22 000 | 6683 (35.5) | 64 946 | 10.3 (10.0 to 10.5) | 0.478, 0.464 to 0.492 | 0.611, 0.590 to 0.632 |
Risk estimates are subdistributional HR or HRs with 95% CI.