Maximum personal annual income quintiles | 1 | 2 | 3 | 4 | 5 | P value |
n=10 663 | n=10 893 | n=10 943 | n=11 370 | n=11 098 | ||
Mean income, € | 1370±1500 | 8363±2301 | 17168±2890 | 29978±4826 | 65109±21 237 | <0.0001 |
Mean cohort entry year | 2012±3 | 2013±3 | 2013±3 | 2014±3 | 2014±3 | <0.0001 |
Demographics | ||||||
Mean age, years | 70.3±2.8 | 70.1±2.8 | 69.8±2.8 | 69.2±2.8 | 69.1±2.8 | <0.0001 |
Female gender | 6401 (60.0) | 5730 (52.2) | 5023 (45.9) | 4368 (38.4) | 2695 (24.3) | <0.0001 |
Highest educational level | <0.0001 | |||||
Category 1 | 7119 (66.8) | 6327 (57.6) | 5308 (48.5) | 4016 (35.3) | 2434 (21.9) | |
Category 2 | 3009 (28.2) | 3626 (33.0) | 3775 (34.5) | 3628 (31.9) | 2388 (21.5) | |
Category 3 | 535 (5.0) | 1038 (9.4) | 1860 (17.0) | 3726 (32.8) | 6276 (56.6) | |
Comorbidities | ||||||
Abnormal liver function | 79 (0.7) | 85 (0.8) | 89 (0.8) | 76 (0.7) | 74 (0.7) | <0.0001 |
Abnormal renal function | 429 (4.0) | 363 (3.3) | 320 (2.9) | 336 (3.0) | 300 (2.7) | <0.0001 |
Alcohol abuse | 714 (6.7) | 606 (5.5) | 512 (4.7) | 434 (3.8) | 347 (3.1) | <0.0001 |
Diabetes | 2849 (26.7) | 2821 (25.7) | 2588 (23.6) | 2493 (21.9) | 2316 (20.9) | <0.0001 |
Dyslipidaemia | 5136 (48.2) | 5577 (50.8) | 5627 (51.4) | 5730 (50.4) | 5517 (49.7) | <0.0001 |
Heart failure | 1977 (18.5) | 1596 (14.5) | 1308 (12.0) | 1091 (9.6) | 868 (7.8) | <0.0001 |
Hypertension | 7820 (73.3) | 8324 (75.8) | 8290 (75.8) | 8363 (73.6) | 8021 (72.3) | <0.0001 |
Prior bleeding | 1084 (10.2) | 1005 (9.2) | 983 (9.0) | 998 (8.8) | 942 (8.5) | <0.0001 |
Prior myocardial infarction | 892 (8.4) | 839 (7.6) | 826 (7.5) | 754 (6.6) | 706 (6.4) | <0.0001 |
Vascular disease | 2850 (26.7) | 2864 (26.1) | 2634 (24.1) | 2577 (22.7) | 2259 (20.4) | <0.0001 |
Dementia | 183 (1.7) | 162 (1.5) | 137 (1.3) | 88 (0.8) | 61 (0.5) | <0.0001 |
Psychiatric disorder | 1983 (18.6) | 1604 (14.6) | 1385 (12.7) | 1164 (10.2) | 925 (8.3) | <0.0001 |
CHA2DS2-VASc score | 3.0±1.0 | 2.9±1.1 | 2.8±1.0 | 2.6±1.0 | 2.4±1.0 | <0.0001 |
OAC before stroke occurrence | 8031 (75.3) | 8943 (81.4) | 8993 (82.2) | 9426 (82.9) | 9252 (83.4) | <0.0001 |
Values denote n (%) or mean (SD).
Vascular disease: prior myocardial infarction and/or peripheral vascular disease.
CHA2DS2-VASc, congestive heart failure, hypertension, age≥75 years, diabetes, history of stroke or TIA, vascular disease, age 65–74 years, sex category (female); OAC, oral anticoagulant.