Characteristics of patients aged <65 years according to their maximum personal annual income quintiles
| Maximum personal annual income quintiles | 1 | 2 | 3 | 4 | 5 | P value |
| n=10 152 | n=10 998 | n=10 784 | n=10 878 | n=10 768 | ||
| Mean income, € | 5445±4123 | 20373±4110 | 31321±2841 | 43806±4838 | 77878±17 258 | <0.0001 |
| Mean cohort entry year | 2011±3 | 2012±3 | 2013±3 | 2013±3 | 2013±3 | <0.0001 |
| Demographics | ||||||
| Mean age, years | 56.4±9.2 | 54.5±10.2 | 53.2±9.8 | 53.0±9.4 | 53.6±8.7 | <0.0001 |
| Female gender | 3675 (36.2) | 4617 (42.0) | 3713 (34.4) | 2512 (23.1) | 1451 (13.5) | <0.0001 |
| Highest educational level | <0.0001 | |||||
| Category 1 | 4648 (45.8) | 3305 (30.1) | 2255 (20.9) | 1720 (15.8) | 1192 (11.1) | |
| Category 2 | 4517 (44.5) | 5838 (53.1) | 5594 (51.9) | 4566 (42.0) | 2824 (26.2) | |
| Category 3 | 987 (9.7) | 1855 (16.9) | 2935 (27.2) | 4592 (42.2) | 6752 (62.7) | |
| Comorbidities | ||||||
| Abnormal liver function | 159 (1.6) | 86 (0.8) | 39 (0.4) | 37 (0.3) | 30 (0.3) | <0.0001 |
| Abnormal renal function | 373 (3.7) | 243 (2.2) | 164 (1.5) | 139 (1.3) | 125 (1.2) | <0.0001 |
| Alcohol abuse | 1901 (18.7) | 846 (7.7) | 496 (4.6) | 442 (4.1) | 300 (2.8) | <0.0001 |
| Diabetes | 2211 (21.8) | 1761 (16.0) | 1367 (12.7) | 1283 (11.8) | 1099 (10.2) | <0.0001 |
| Dyslipidaemia | 3324 (32.7) | 3367 (30.6) | 2913 (27.0) | 2917 (26.8) | 2905 (27.0) | <0.0001 |
| Heart failure | 1525 (15.0) | 1055 (9.6) | 718 (6.8) | 688 (6.3) | 544 (5.1) | <0.0001 |
| Hypertension | 6307 (62.1) | 6599 (60.0) | 6016 (55.8) | 5868 (53.9) | 5631 (52.3) | <0.0001 |
| Prior bleeding | 1051 (10.4) | 646 (5.9) | 544 (5.0) | 507 (4.7) | 445 (4.1) | <0.0001 |
| Prior myocardial infarction | 643 (6.3) | 526 (4.8) | 424 (3.9) | 391 (3.6) | 341 (3.2) | <0.0001 |
| Vascular disease | 1869 (18.4) | 1519 (13.8) | 1187 (11.0) | 1143 (10.5) | 977 (9.1) | <0.0001 |
| Dementia | 74 (0.7) | 29 (0.3) | 9 (0.1) | 10 (0.1) | 8 (0.1) | <0.0001 |
| Psychiatric disorder | 3740 (36.8) | 2099 (19.1) | 1403 (13.0) | 1138 (10.5) | 758 (7.0) | <0.0001 |
| CHA2DS2-VASc score | 1.5±1.1 | 1.4±1.0 | 1.2±0.9 | 1.0±0.9 | 0.9±0.9 | <0.0001 |
| OAC before stroke occurrence | 6017 (59.3) | 6639 (60.4) | 6133 (56.9) | 6118 (56.2) | 5956 (55.3) | <0.0001 |
Values denote n (%) or mean (SD). Vascular disease: prior myocardial infarction and/or peripheral vascular disease.
CHA2DS2-VASc, congestive heart failure, hypertension, age≥75 years, diabetes, history of stroke or TIA, vascular disease, age 65–74 years, sex category (female); OAC, oral anticoagulant.