Study sample characteristics
| Female | Male | Overall | |
| Sample size, n (%) | 104945 (45.5) | 125846 (54.5) | 230791 (100) |
| Age, mean (SD) | 50.96 (5.55) | 54.46 (7.04) | 52.87 (6.64) |
| Depression, n (%) | 17676 (16.8) | 15604 (12.4) | 33280 (14.4) |
| Polygenic Risk Score, mean (SD) | 26.03 (3.41) | 26.08 (3.41) | 26.06 (3.41) |
| Employment Category, n (%) | |||
| In paid employment | 83292 (79.4) | 90303 (71.8) | 173595 (75.2) |
| Not in paid employment | 20791 (19.8) | 34507 (27.4) | 55298 (24.0) |
| Early retirement | 6768 (6.4) | 24036 (19.1) | 30804 (13.3) |
| Sick/disabled | 4978 (4.7) | 6848 (5.4) | 11826 (5.1) |
| Caring for home/family | 7534 (7.2) | 1080 (0.9) | 8614 (3.7) |
| Unemployed | 1640 (1.6) | 3558 (2.8) | 5198 (2.3) |
| NA | 20013 (19.1) | 31985 (25.4) | 51998 (22.5) |
| Hours worked weekly, mean (SD) | 32.28 (11.60) | 40.34 (11.07) | 36.47 (12.02) |
| Townsend Deprivation Index, mean (SD) | −1.49 (2.93) | −1.48 (3.02) | −1.48 (2.98) |
| Household Income, n (%) | |||
| Less than 18,000 | 13707 (13.1) | 18055 (14.3) | 31762 (13.8) |
| 18,000 to 30,999 | 19968 (19.0) | 25266 (20.1) | 45234 (19.6) |
| 31,000 to 51,999 | 28012 (26.7) | 33279 (26.4) | 61291 (26.6) |
| 52,000 to 100,000 | 24485 (23.3) | 29693 (23.6) | 54178 (23.5) |
| Greater than 100,000 | 6303 (6.0) | 8030 (6.4) | 14333 (6.2) |
| NA | 12470 (11.9) | 11523 (9.2) | 23993 (10.4) |
| Highest educational attainment, n (%) | |||
| None of the below | 9321 (8.9) | 17023 (13.5) | 26344 (11.4) |
| CSEs or equivalent | 5709 (5.4) | 5035 (4.0) | 10744 (4.7) |
| O levels/GCSEs or equivalent | 15486 (14.8) | 12937 (10.3) | 28423 (12.3) |
| A levels/AS levels or equivalent | 6896 (6.6) | 6562 (5.2) | 13458 (5.8) |
| NVQ or HND or HNC or equivalent | 13834 (13.2) | 20850 (16.6) | 34684 (15.0) |
| Other professional qualifications e.g. nursing, teaching | 15518 (14.8) | 18354 (14.6) | 33872 (14.7) |
| College or University degree | 37508 (35.7) | 44076 (35.0) | 81584 (35.3) |
| NA | 673 (0.6) | 1009 (0.8) | 1682 (0.7) |
Employment category: respondents could endorse multiple categories. The ‘not in paid employment’ category is a composite of the listed non-employment categories. The ‘in paid employment’ and ‘not in paid employment’ sum to less than 100% due to some participants giving invalid answers for the employment question. The numbers in this table are the same as in our previous body mass index employment study.12
NA, not applicable.