Characteristics of patients with SARS-CoV-2 included in the multivariable logistic regression model, March 2020–January 2021, England
| Variable | Levels | Died within 28 days | Did not die within 28 days | Total | Univariable OR (95% CI) |
| Age (years) | Median (IQR) | 82.0 (74.0–89.0) | 39.0 (25.0–54.0) | 44.0 (27.0–62.0) | 1.12 (1.12 to 1.13) |
| Sex | Female | 2742 (12.2) | 19 745 (87.8) | 22 487 | Reference |
| Male | 3258 (16.7) | 16 255 (83.3) | 19 513 | 1.44 (1.37 to 1.52) | |
| Ethnicity | White | 5327 (16.3) | 27 298 (83.7) | 32 625 | Reference |
| Asian | 419 (7.2) | 5400 (92.8) | 5819 | 0.4 (0.36 to 0.44) | |
| Black | 197 (10.1) | 1763 (89.9) | 1960 | 0.57 (0.49 to 0.66) | |
| Other | 57 (3.6) | 1539 (96.4) | 1596 | 0.19 (0.14 to 0.25) | |
| Residence | Private home | 4137 (10.7) | 34 476 (89.3) | 38 613 | Reference |
| Residential LTCF | 855 (50.9) | 824 (49.1) | 1679 | 8.65 (7.82 to 9.57) | |
| Nursing LTCF | 1008 (59.0) | 700 (41.0) | 1708 | 12.0 (10.84 to 13.29) | |
| IMD decile | 1 | 666 (13.8) | 4173 (86.2) | 4839 | 0.94 (0.83 to 1.07) |
| 2 | 713 (14.1) | 4341 (85.9) | 5054 | 0.97 (0.85 to 1.09) | |
| 3 | 671 (13.7) | 4226 (86.3) | 4897 | 0.93 (0.82 to 1.06) | |
| 4 | 606 (13.6) | 3844 (86.4) | 4450 | 0.93 (0.82 to 1.05) | |
| 5 | 611 (14.2) | 3696 (85.8) | 4307 | 0.97 (0.85 to 1.11) | |
| 6 | 542 (13.3) | 3524 (86.7) | 4066 | 0.90 (0.79 to 1.03) | |
| 7 | 588 (15.3) | 3266 (84.7) | 3854 | 1.06 (0.93 to 1.21) | |
| 8 | 570 (15.7) | 3070 (84.3) | 3640 | 1.09 (0.96 to 1.25) | |
| 9 | 549 (15.4) | 3014 (84.6) | 3563 | 1.07 (0.94 to 1.22) | |
| 10 | 484 (14.5) | 2846 (85.5) | 3330 | Reference | |
| Region | South West | 337 (14.5) | 1994 (85.5) | 2331 | Reference |
| East Midlands | 555 (15.9) | 2937 (84.1) | 3492 | 1.12 (0.97 to 1.30) | |
| East of England | 739 (15.3) | 4090 (84.7) | 4829 | 1.07 (0.93 to 1.23) | |
| London | 865 (10.9) | 7060 (89.1) | 7925 | 0.72 (0.63 to 0.83) | |
| North East | 312 (15.3) | 1729 (84.7) | 2041 | 1.07 (0.90 to 1.26) | |
| North West | 954 (14.4) | 5675 (85.6) | 6629 | 0.99 (0.87 to 1.14) | |
| South East | 907 (15.3) | 5031 (84.7) | 5938 | 1.07 (0.93 to 1.22) | |
| West Midlands | 770 (16.1) | 4016 (83.9) | 4786 | 1.13 (0.99 to 1.30) | |
| Yorkshire and Humber | 561 (13.9) | 3468 (86.1) | 4029 | 0.96 (0.83 to 1.11) | |
| Month | March 2020 | 507 (66.0) | 261 (34.0) | 768 | 36.08 (21.41 to 65.92) |
| April 2020 | 1132 (55.2) | 917 (44.8) | 2049 | 22.93 (13.82 to 41.42) | |
| May 2020 | 301 (33.0) | 612 (67.0) | 913 | 9.13 (5.44 to 16.65) | |
| June 2020 | 78 (23.9) | 248 (76.1) | 326 | 5.84 (3.32 to 11.01) | |
| July 2020 | 16 (8.7) | 168 (91.3) | 184 | 1.77 (0.84 to 3.77) | |
| August 2020 | 14 (5.1) | 260 (94.9) | 274 | Reference | |
| September 2020 | 67 (5.2) | 1210 (94.8) | 1277 | 1.03 (0.59 to 1.93) | |
| October 2020 | 403 (7.7) | 4847 (92.3) | 5250 | 1.54 (0.93 to 2.80) | |
| November 2020 | 673 (10.2) | 5893 (89.8) | 6566 | 2.12 (1.28 to 3.83) | |
| December 2020 | 1099 (10.2) | 9702 (89.8) | 10 801 | 2.10 (1.27 to 3.79) | |
| January 2021 | 1710 (12.6) | 11 882 (87.4) | 13 592 | 2.67 (1.62 to 4.81) |
IMD, Index of Multiple Deprivation; LTCF, long-term care facility.