Table 4

Adjusted association estimates of antibiotic-resistant from case–control reports

Infection siteAuthorAntibioticBacteriaMeasure of associationAdjustment
Urinary tract infectionVinken et al 15 Nitrofurantoin; trimethoprim; fosfomycin; ciprofloxacin; amoxicillin/clavulanic acid and/or trimethoprim/sulfamethoxazol Escherichia coli; Enterococcus spp; Klebsiella pneumoniae; Proteus mirabilis; Klebsiella oxytoca; Pseudomonas aeruginosa; and others 32 speciesOR: 0.90 (0.40 to 1.80)Age; hospital admission in preceding 12 months; elderly home resident; use of antibiotics in preceding 12 months; urinary tract infection in preceding 12 months; micturition complaints in preceding 6 weeks
Colodner et al 43 Extended-spectrum beta-lactamases Escherichia coli or Klebsiella OR: 2.57 (1.20 to 5.51)Age; Escherichia coli infection; infection; duration of antibiotic treatment; hospitalisation in the last 3 months; gender; age more than 60; underlying diseases (cardiovascular; gastrointestinal; genitourinary; recurrent urinary tract infection; neurological; malignancies)
Wright et al 75 Trimethoprim-sulfamethoxazoleColiform (Escherichia coli; Proteus mirabilis; Klebsiella pneumoniae; Enterobacter species; Citrobacter freundi; Providencia species and Morganella morganii)OR: 3.10 (1.20 to 8.40)Age; use of catheter; history of recurrent urinary tract infection; urological abnormality; neurological abnormality; recently in hospital; current antibiotic; current trimethoprim-sulfamethoxazole use
Park et al 45 Amikacin; gentamicin; tobramycin; ciprofloxacin; levofloxacin; amoxicillun-clavulanate; piperacillin-tazobactam; trimethoprim-sulfamethoxazole; fluoroquinolones; aminoglycosides Escherichia coli OR: 1.69 (0.78 to 3.44)Age >55; sex; urinary tract abnormalities; acute pyelonephritis recurrence and antibiotic use within the previous year
Anesi et al 66 Extended-spectrum cephalosporinExtended-spectrum cephalosporin-resistant Enterobacteriaceae: Escherichia coli (76%); Klebsiella species (13%) and Enterobacter species (9%)OR: 2.91 (1.32 to 6.41)Age; presentation to emergency department; trimethoprim sulfamethoxazole; receipt within prior 6 months
Søraas et al 49 Extended-spectrum beta-lactamases (mecillinam; macrolides; tetracyclines; fluoroquinolones; nitrofurantoin; trimethoprim or trimethoprim/sulfamethoxazole; b-lactams except mecillinam; methenamine hippurate Escherichia coli or Klebsiella OR: 3.20 (1.00 to 11.00)Travel destinations; recreational swimming past year; fish meals per week; dinner at restaurant >2/month; close occupational contact with humans; bath or shower <2/week; digestive problems
Respiratory tract infectionKim et al 46 Carbapenems (meropenem; imipenem)Gram-negative bacteria or Stenotrophomonas maltophili OR: 2.82 (1.25 to 6.38)Neurological disease; Macabe and Jackson classification; ventilator-associated pneumonia; APACHE II; radiological score; prior antibiotic usage