Characteristics of Sister Study participants according to Area Deprivation Index (ADI) (n=47 329) (N (%) or mean (SD))
| ADI | ≤10% | 11%–20% | 21%–35% | 36%–55% | >55% |
| (n=8837) | (n=8342) | (n=10 177) | (n=9910) | (n=10 063) | |
| Age (years) | |||||
| ≤45 | 1436 (16) | 1490 (18) | 1600 (16) | 1433 (14) | 1512 (15) |
| 46–50 | 1400 (16) | 1417 (17) | 1691 (17) | 1668 (17) | 1623 (16) |
| 51–55 | 1810 (20) | 1668 (20) | 2108 (21) | 1936 (20) | 2024 (20) |
| 56–60 | 1694 (19) | 1555 (19) | 1977 (19) | 1946 (20) | 1856 (18) |
| 61–65 | 1325 (15) | 1148 (14) | 1418 (14) | 1476 (15) | 1543 (15) |
| >65 | 1172 (13) | 1064 (13) | 1383 (14) | 1451 (15) | 1505 (15) |
| Self-reported race/ethnicity | |||||
| Non-Hispanic white | 7979 (90) | 7393 (89) | 8796 (86) | 8359 (84) | 7737 (77) |
| Non-Hispanic black | 337 (4) | 503 (6) | 800 (8) | 1000 (10) | 1598 (16) |
| Hispanic | 263 (3) | 247 (3) | 351 (3) | 295 (3) | 395 (4) |
| Other* | 258 (3) | 199 (2) | 230 (2) | 256 (3) | 333 (3) |
| Educational attainment | |||||
| High school or less | 549 (6) | 938 (11) | 1498 (15) | 1842 (19) | 2274 (23) |
| Some college | 2123 (24) | 2570 (31) | 3400 (33) | 3758 (38) | 4128 (41) |
| Bachelor’s degree or more | 6165 (70) | 4834 (58) | 5279 (52) | 4310 (43) | 3661 (36) |
| Annual household income | |||||
| ≤US$49 999 | 788 (9) | 1221 (15) | 2197 (22) | 3046 (31) | 4416 (44) |
| US$50 000–US$99 999 | 2615 (30) | 3352 (40) | 4619 (45) | 4659 (47) | 4243 (42) |
| ≥US$100 000 | 5434 (61) | 3769 (45) | 3361 (33) | 2205 (22) | 1404 (14) |
| BMI (kg/m2) | |||||
| BMI <30 | 7187 (81) | 6283 (75) | 7032 (69) | 6507 (66) | 6057 (60) |
| BMI≥30 | 1645 (19) | 2058 (25) | 3143 (31) | 3401 (34) | 4000 (40) |
| Missing | 5 | 1 | 2 | 2 | 6 |
| Hypertension† | |||||
| Non-hypertensive | 6621 (75) | 5835 (70) | 6859 (67) | 6292 (63) | 5955 (59) |
| Hypertensive | 2216 (25) | 2507 (30) | 3318 (33) | 3618 (37) | 4108 (41) |
| SBP (mm Hg)‡ | 116 (16) | 118 (17) | 119 (17) | 121 (17) | 123 (17) |
| DBP (mm Hg)‡ | 74 (10) | 74 (11) | 75 (11) | 76 (11) | 77 (11) |
| PP (mm Hg)§ | 42 (10) | 43(10) | 44 (10) | 45 (11) | 46 (11) |
| MAP (mm Hg) § | 88 (12) | 89 (12) | 90 (12) | 91 (12) | 93 (12) |
High ADI represents high deprivation.
*Others include non-Hispanic Asian/Pacific Islanders, non-Hispanic American Indians and non-Hispanic other.
†Hypertension was defined as SBP ≥140 mm Hg or DBP ≥90 mm Hg or taking medications.
‡For participants on antihypertensive medications, measured blood pressure was corrected by adding 15 mm Hg to SBP and 10 mm Hg to DBP.
§PP=SBP DBP; MAP=1/3(SBP) +2/3(DBP).
BMI, body mass index; DBP, diastolic blood pressure; MAP, mean arterial pressure; PP, pulse pressure; SBP, systolic blood pressure.