Table 2

Descriptive statistics for full cohort (derivation and validation populations combined)

Full cohort
Diagnosed with dementiaNot diagnosed with dementia*
Total participants16 998534 346
Female (%)8903 (52)267 340 (50)
Total follow-up time (person-years)279 7205 546 489
Median follow-up time (years)17.09.7
Median year at start of follow-up†19982007
Deprivation quintile (%)
 1 – Most deprived3769 (22)95 381 (18)
 23106 (18)98 448 (18)
 33348 (20)113 807 (21)
 43048 (18)105 032 (20)
 5 – Least deprived3727 (22)121 678 (23)
Polypharmacy (%)2602 (15)79 801 (15)
Ever smoker (%)12 207 (72)353 090 (66)
  • *Did not develop dementia by the end of follow-up. Smoking was defined as being an ever- versus never-smoker. Polypharmacy was defined as being prescribed ≥10 different drugs during the first year of the observation period (from age 60–61 years).

  • †Median year at age 60 years.