Difference in change from before to after invitation in the invitation group relative to the control group
| COS-CRC scales (range of values) | Mean change unadjusted (99% CI) | P value* | Mean change adjusted (99% CI) | P value* |
| Dejection (0–18) | −0.18 (−0.94 to 0.58) | 0.54 | −0.23 (−0.98 to 0.52) | 0.42 |
| Anxiety (0–21) | −0.28 (−1.11 to 0.55) | 0.38 | −0.33 (−1.14 to 0.48) | 0.29 |
| Behaviour (0–21) | −0.37 (−1.27 to 0.54) | 0.30 | −0.40 (−1.28 to 0.48) | 0.24 |
| Sleep (0–12) | −0.37 (−1.07 to 0.33) | 0.18 | −0.39 (−1.08 to 0.30) | 0.14 |
| Introvert (0–15) | −0.20 (−0.83 to 0.43) | 0.41 | −0.24 (−0.86 to 0.38) | 0.33 |
| Change in body perception (0–9) | −0.37 (−0.77 to 0.03) | 0.017 | −0.39 (−0.78 to −0.0080) | 0.0085 |
| Fear and powerlessness (0–12) | −0.22 (−0.76 to 0.32) | 0.29 | −0.24 (−0.77 to 0.29) | 0.24 |
| Change in perception of own age (0–6) | −0.25 (−0.59 to 0.089) | 0.056 | −0.27 (−0.60 to 0.061) | 0.036 |
| Emotional reactions (0–6) | −0.17 (−0.42 to 0.069) | 0.065 | −0.18 (−0.42 to 0.049) | 0.042 |
| COS-CRC single items | ||||
| Negative impact on sexuality (0–3) | 0.054 (−0.18 to 0.29) | 0.57 | 0.066 (−0.18 to 0.31) | 0.49 |
| Life-style changes (0–3) | −0.011 (−0.15 to 0.13) | 0.84 | −0.014 (−0.16 to 0.13) | 0.80 |
*P value of difference in mean increase between the study groups.
COS-CRC, consequences of screening in colorectal cancer.