Table 2

Survey Cox regression model of factors associated with postnatal (6 weeks to 18 months) MTCT and ‘MTCT-or-death’

Postnatal MTCT*‡‘MTCT-or-death’*
CharacteristicsAdjusted HR (95% CI)P valueAdjusted HR (95% CI)P value
Maternal
Maternal age1.0 (0.9–1.1)0.821.0 (1.0–1.0)0.70
Married/cohabiting mother1.1 (0.5–2.2)0.810.9 (0.6–1.3)0.47
Maternal ART-use†0.6 (0.3–1.2)†0.150.8 (0.6–1.2)†0.32
Socio-economic (at baseline)
No transport available to clinic0.6 (0.3–1.1)0.090.9 (0.6–1.4)0.64
Unpiped water1.8 (0.8–4.1)0.151.4 (0.9–2.2)0.16
No flush toilet0.7 (0.3–1.3)0.250.9 (0.6–1.4)0.90
Did not run out of food1.0 (0.4–2.3)0.951.7 (1.0–2.9)0.06
No refrigerator1.0 (0.3–3.2)1.001.7 (1.1–2.9)0.03
Infant
EBF ref: formula2.3 (1.0–5.2)0.0490.9 (0.6–1.3)†0.55
MF ref: formula3.7 (1.2–11.4)0.031.6 (0.8–2.9)†0.18
Infant NVP use at 6 weeks0.4 (0.1–1.0)0.060.4 (0.2–0.9)0.02
Infant male gender0.8 (1.0–5.6)0.061.3 (0.8–1.9)0.24
No other infant medication use, other than NVP0.7 (0.3–1.8)0.431.3 (0.7–2.4)0.45
Health service access/quality
Mother not tested for CD42.7 (1.5–5.6)0.002**1.3 (0.9–2.0)0.18
No documentation of maternal HIV-status on infants’ RTHB2.2 (1.0–4.7)0.04**1.5 (0.9–2.4)0.09
Mother did not receive ARV during pregnancy1.2 (0.6–2.4)0.561.2 (0.8–1.8)0.37
Birth location not in a clinic0.6 (0.4–1.9)0.771.1 (0.7–1.6)0.70
  • *A total of 2240 observations used with 34 events. Wald statistic <0.0001; 2533 observations used with 96 events; Wald statistic=0.0002.

  • †Time-dependent covariate. All remaining variables were from the baseline interview.

  • ‡Excludes infections detected at 6 weeks post-delivery **p<0.05.

  • ART, antiretroviral therapy; ARV, antiretroviral drug; MTCT, mother-to-child transmission of HIV,NVP, nevirapine, EBF—exclusive breastfeeding, RTHB—Road-to-Health