Age-stratified differences† in mean biomarker levels in KYH compared with Tromsø 7 by sex, adjusted for age (within strata)
| Men | Women | |||||
|---|---|---|---|---|---|---|
| 40–54 years old | 55–69 years old | P value for interaction | 40–54 years old | 55–69 years old | p-value for interaction | |
| Total cholesterol | −0.27 (−0.36, −0.19) | −0.17 (−0.25, −0.09) | 0.077 | 0.05 (−0.01, 0.12) | −0.18 (−0.25, −0.12) | <0.001 |
| HDL cholesterol | −0.01 (−0.04, 0.02) | −0.08 (−0.11, −0.05) | 0.002 | −0.03 (−0.06, 0.00) | −0.22 (−0.25, −0.19) | <0.001 |
| LDL cholesterol | −0.33 (−0.41, −0.25) | −0.20 (−0.27, −0.13) | 0.02 | 0.01 (−0.06, 0.07) | −0.06 (−0.12, 0.00) | 0.157 |
| Triglycerides‡§ | −0.01 (−0.06, 0.04) | 0.07 (0.02, 0.11) | 0.012 | 0.12 (0.09, 0.16) | 0.19 (0.15, 0.22) | 0.016 |
| hsCRP‡ | 0.18 (0.10, 0.25) | 0.38 (0.31, 0.45) | <0.001 | 0.19 (0.13, 0.26) | 0.41 (0.34, 0.47) | <0.001 |
| NT-proBNP | 0.33 (0.19, 0.48) | 0.49 (0.39, 0.59) | 0.081 | 0.07 (−0.03, 0.17) | 0.40 (0.32, 0.47) | <0.001 |
| hs-cTnT‡ | 0.35 (0.27, 0.43) | 0.36 (0.31, 0.42) | 0.788 | 0.44 (0.38, 0.49) | 0.57 (0.53, 0.61) | <0.001 |
†Values in KYH minus those in Tromsø 7.
‡Analysis is based on ln-transformed values.
§The models for triglycerides were additionally adjusted for fasting time because of differences in mean fasting time in two studies.
HDL, high-density lipoprotein; hsCRP, high-sensitivity C-reactive protein; hs-cTnT, high-sensitivity cardiac troponin T; KYH, Know Your Heart; LDL, low-density lipoprotein; NT-proBNP, N-terminal pro-b-type natriuretic peptide.