Table 5

Parental alcohol misuse (ages 0–19) in relation to the risk of alcohol misuse in adulthood (ages 20–63). Results from Cox regression analysis with four-way decomposition by school performance in grade 12 (age 19). Based on Sample C (n=6777)

Alcohol misuse in adulthood (ages 20–63)
Model 1*Model 2†
EstimateP value95% CIEstimateP value95% CI
Parental alcohol misuse (ages 0–19)
Total excess relative risk (tereri)1.800.0400.08, 3.531.450.065−0.09, 3.00
 Four-way decomposition by school performance in grade 12 (age 19)
  Excess relative risk due to neither mediation nor interaction (ereri_cde)1.260.290−1.07, 3.611.200.313−1.13, 3.53
  Excess relative risk due to interaction only (ereri_intref)0.380.648−1.24, 2.010.190.806−1.32, 1.69
  Excess relative risk due to mediated interaction (ereri_intmed)0.100.650−0.34, 0.540.030.807−0.23, 0.29
  Excess relative risk due to mediation only (ereri_pie)0.060.0280.01, 0.110.030.123−0.01, 0.07
Total effect relative risk ratio (tereria)2.800.0011.08, 4.532.450.0020.91, 4.00
 Four-way decomposition by school performance in grade 12 (age 19)
  Proportion due to neither mediation nor interaction (p_cde)0.700.215−0.41, 1.810.830.186−0.40, 2.05
  Proportion due to interaction only (p_intref)0.210.638−0.67, 1.090.130.807−0.91, 1.17
  Proportion due to mediated interaction (p_intmed)0.060.640−0.18, 0.290.020.808−0.16, 0.20
  Proportion due to mediation only (p_pie)0.030.128−0.01, 0.070.020.225−0.01, 0.06
  Overall proportion due to mediation (op_m)0.090.465−0.15, 0.330.040.648−0.14, 0.23
  Overall proportion due to interaction (op_ati)0.270.638−0.84, 1.380.150.807−1.07, 1.37
  Overall proportion eliminated (op_e)0.300.597−0.81, 1.410.170.781−1.05, 1.40
  • *Unadjusted.

  • †Adjusted for gender, parental social class, parental educational level and parental income.

  • Component names, as specified in the med4way output, are presented in the table as italicised.