Table 4

Parental alcohol misuse (ages 0–19) in relation to the risk of alcohol misuse in adulthood (ages 20–63). Results from Cox regression analysis with four-way decomposition by school performance in grade 9 (age 16). Based on Sample B (n=13 021)

Alcohol misuse in adulthood (ages 20–63)
Model 1*Model 2†
EstimateP value95% CIEstimateP value95% CI
Parental alcohol misuse (ages 0–19)
Total excess relative risk (tereri)1.540.0000.92, 2.171.490.0000.77, 2.20
 Four-way decomposition by school performance in grade 9 (age 16)
  Excess relative risk due to neither mediation nor interaction (ereri_cde)0.120.0110.25, 1.991.230.0160.23, 2.23
  Excess relative risk due to interaction only (ereri_intref)0.190.511−0.38, 0.760.110.577−0.28, 0.49
  Excess relative risk due to mediated interaction (ereri_intmed)0.080.511−0.15, 0.310.050.579−0.11, 0.20
  Excess relative risk due to mediation only (ereri_pie)0.160.0000.11, 0.200.100.0000.06, 0.15
Total effect relative risk ratio (tereria)2.540.0001.92, 3.172.490.0001.77, 3.20
 Four-way decomposition by school performance in grade 9 (age 16)
  Proportion due to neither mediation nor interaction (p_cde)0.730.0040.23, 1.220.830.0000.43, 1.22
  Proportion due to interaction only (p_intref)0.120.499−0.23, 0.480.070.594−0.20, 0.34
  Proportion due to mediated interaction (p_intmed)0.050.500−0.09, 0.190.030.595−0.08, 0.14
  Proportion due to mediation only (p_pie)0.100.0000.05, 0.150.070.0010.03, 0.11
  Overall proportion due to mediation (op_m)0.150.0420.01, 0.300.100.133−0.03, 0.23
  Overall proportion due to interaction (op_ati)0.170.499−0.33, 0.670.100.594−0.28, 0.48
  Overall proportion eliminated (op_e)0.270.279−0.22, 0.770.170.390−0.22, 0.57
  • *Unadjusted.

  • †Adjusted for gender, parental social class, parental educational level and parental income.

  • Component names, as specified in the med4way output, are presented in the table as italicised.