Association of hsCRP (quartiles) with all-cause mortality over a mean follow-up of 8.0±1.1 years
| Models | Total N=14 238 (100%) | Deaths n=444 (3.12%) | hsCRP (mg/L) | |||
| Quartile 1 HR (reference) | Quartile 2 HR (95% CI) | Quartile 3 HR (95% CI) | Quartile 4 HR (95% CI) | |||
| Model 1* | 1.0 | 1.43 (1.05 to 1.96) | 1.65 (1.22 to 2.23) | 2.23 (1.67 to 2.98) | ||
| Model 2† | 1.0 | 1.45 (1.06 to 1.99) | 1.74 (1.28 to 2.35) | 2.47 (1.84 to 3.30) | ||
| Model 3‡ | 1.0 | 1.47 (1.07 to 2.02) | 1.75 (1.29 to 2.39) | 2.43 (1.80 to 3.30) | ||
| Model 4§ | 1.0 | 1.45 (1.05 to 2.01) | 1.61 (1.17 to 2.22) | 2.08 (1.52 to 2.85) | ||
| Model 5¶ | 1.0 | 1.45 (1.05 to 2.01) | 1.54 (1.11 to 2.13) | 1.95 (1.42 to 2.69) | ||
*Model 1: adjusted for age.
†Model 2: model 1 and sex.
‡Model 3: model 2 and ethnicity and body mass index.
§Model 4: model 3 and level of education, alcohol consumption, smoking status, physical activity level, and fruits and vegetables consumption.
¶Model 5: model 4 and systolic blood pressure, use of antihypertensive drugs, diabetes mellitus, depression, chronic obstructive pulmonary disease, cardiovascular disease and cancer.
hsCRP, high-sensitivity C reactive protein.