Table 4

HRs (95% CI) of risk of death from all causes according to standardised scores for attitudes to ageing at age 72 years, adjusted for brain-PAD and covariates (n=622)

Adjustments	Attitudes to ageing scales (per SD)
Adjustments	Physical change	†p/p^FDR	Psychosocial loss	†p/p^FDR	Psychological growth	†p/p^FDR
Age and sex	0.64 (0.53 to 0.77)	<0.001/0.003	1.44 (1.21 to 1.70)	<0.001/0.003	0.88 (0.73 to 1.06)	0.169/0.195
Age, sex and brain-PAD	0.65 (0.54 to 0.78)	<0.001/0.003	1.42 (1.20 to 1.69)	<0.001/0.003	0.89 (0.74 to 1.07)	0.217/0.235
Age, sex and education	0.65 (0.54 to 0.79)	<0.001/0.003	1.41 (1.18 to 1.67)	<0.001/0.003	0.84 (0.70 to 1.02)	0.076/0.106
As above plus brain-PAD	0.67 (0.56 to 0.81)	<0.001/0.003	1.39 (1.17 to 1.66)	<0.001/0.003	0.84 (0.70 to 1.02)	0.085/0.116
Age, sex, smoking and alcohol	0.66 (0.55 to 0.80)	<0.001/0.003	1.36 (1.15 to 1.61)	<0.001/0.003	0.88 (0.73 to 1.06)	0.165/0.194
Age, sex, smoking and alcohol plus brain-PAD	0.68 (0.56 to 0.81)	<0.001/0.003	1.35 (1.14 to 1.60)	0.001/0.002	0.89 (0.74 to 1.06)	0.194/0.133
Age, sex, chronic disease and walking speed	0.69 (0.57 to 0.84)	<0.001/0.003	1.34 (1.12 to 1.60)	0.001/0.002	0.87 (0.73 to 1.05)	0.140/0.168
Age, sex, chronic disease and walking speed plus brain-PAD	0.71 (0.58 to 0.86)	<0.001/0.003	1.34 (1.12 to 1.60)	0.001/0.002	0.88 (0.73 to 1.06)	0.180/0.204
Age, sex, anxiety and depression	0.68 (0.56 to 0.82)	<0.001/0.003	1.36 (1.11 to 1.67)	0.003/0.006	0.93 (0.77 to 1.13)	0.477/0.492
Age, sex, anxiety and depression plus brain-PAD	0.68 (0.56 to 0.82)	<0.001/0.003	1.37 (1.12 to 1.67)	0.002/0.004	0.94 (0.78 to 1.13)	0.489/0.497
All*	0.76 (0.62 to 0.92)	0.006/0.011	1.27 (1.04 to 1.55)	0.020/0.033	0.88 (0.73 to 1.07)	0.196/0.216

*Age, sex, brain-PAD, educational attainment, total number of chronic diseases, time taken to walk 6 metres, smoking status, frequency of alcohol consumption, HADS anxiety score, HADS depression score.
†p^FDR is the p value corrected for multiple comparisons using the False Discovery Rate.
Brain-PAD, brain-predicted age difference; HADS, Hospital Anxiety and Depression Scale.